Targeting fibroblast growth factor receptors to combat aggressive ependymoma

Ependymomas (EPN) are central nervous system tumors comprising both aggressive and more benign molecular subtypes. However, therapy of the high-risk subtypes posterior fossa group A (PF-A) and supratentorial RELA-fusion positive (ST-RELA) is limited to gross total resection and radiotherapy, as effe...

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Detalles Bibliográficos
Autores principales: Lötsch, Daniela, Kirchhofer, Dominik, Englinger, Bernhard, Jiang, Li, Okonechnikov, Konstantin, Senfter, Daniel, Laemmerer, Anna, Gabler, Lisa, Pirker, Christine, Donson, Andrew M., Bannauer, Peter, Korbel, Pia, Jaunecker, Carola N., Hübner, Jens-Martin, Mayr, Lisa, Madlener, Sibylle, Schmook, Maria T., Ricken, Gerda, Maaß, Kendra, Grusch, Michael, Holzmann, Klaus, Grasl-Kraupp, Bettina, Spiegl-Kreinecker, Sabine, Hsu, Jennifer, Dorfer, Christian, Rössler, Karl, Azizi, Amedeo A., Foreman, Nicholas K., Peyrl, Andreas, Haberler, Christine, Czech, Thomas, Slavc, Irene, Filbin, Mariella G., Pajtler, Kristian W., Kool, Marcel, Berger, Walter, Gojo, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270873/
https://www.ncbi.nlm.nih.gov/pubmed/34046693
http://dx.doi.org/10.1007/s00401-021-02327-x

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