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Structure of Tau filaments in Prion protein amyloidoses

In human neurodegenerative diseases associated with the intracellular aggregation of Tau protein, the ordered cores of Tau filaments adopt distinct folds. Here, we analyze Tau filaments isolated from the brain of individuals affected by Prion-Protein cerebral amyloid angiopathy (PrP-CAA) with a nons...

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Detalles Bibliográficos
Autores principales: Hallinan, Grace I., Hoq, Md Rejaul, Ghosh, Manali, Vago, Frank S., Fernandez, Anllely, Garringer, Holly J., Vidal, Ruben, Jiang, Wen, Ghetti, Bernardino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270882/
https://www.ncbi.nlm.nih.gov/pubmed/34128081
http://dx.doi.org/10.1007/s00401-021-02336-w