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Co-factor-free aggregation of tau into seeding-competent RNA-sequestering amyloid fibrils
Pathological aggregation of the protein tau into insoluble aggregates is a hallmark of neurodegenerative diseases. The emergence of disease-specific tau aggregate structures termed tau strains, however, remains elusive. Here we show that full-length tau protein can be aggregated in the absence of co...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270918/ https://www.ncbi.nlm.nih.gov/pubmed/34244499 http://dx.doi.org/10.1038/s41467-021-24362-8 |