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IGF-1 protects against angiotensin II-induced cardiac fibrosis by targeting αSMA

The insulin-like growth factor 1 receptor (IGF-1R) signaling in cardiomyocytes is implicated in physiological hypertrophy and myocardial aging. Although fibroblasts account for a small amount of the heart, they are activated when the heart is damaged to promote cardiac remodeling. However, the role...

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Detalles Bibliográficos
Autores principales:	Ock, Sangmi, Ham, Woojin, Kang, Chae Won, Kang, Hyun, Lee, Wang Soo, Kim, Jaetaek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270920/ https://www.ncbi.nlm.nih.gov/pubmed/34244467 http://dx.doi.org/10.1038/s41419-021-03965-5

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