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The evolution of convex trade-offs enables the transition towards multicellularity
The evolutionary transition towards multicellular life often involves growth in groups of undifferentiated cells followed by differentiation into soma and germ-like cells. Theory predicts that germ soma differentiation is facilitated by a convex trade-off between survival and reproduction. However,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270964/ https://www.ncbi.nlm.nih.gov/pubmed/34244514 http://dx.doi.org/10.1038/s41467-021-24503-z |
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author | Bernardes, Joana P. John, Uwe Woltermann, Noemi Valiadi, Martha Hermann, Ruben J. Becks, Lutz |
author_facet | Bernardes, Joana P. John, Uwe Woltermann, Noemi Valiadi, Martha Hermann, Ruben J. Becks, Lutz |
author_sort | Bernardes, Joana P. |
collection | PubMed |
description | The evolutionary transition towards multicellular life often involves growth in groups of undifferentiated cells followed by differentiation into soma and germ-like cells. Theory predicts that germ soma differentiation is facilitated by a convex trade-off between survival and reproduction. However, this has never been tested and these transitions remain poorly understood at the ecological and genetic level. Here, we study the evolution of cell groups in ten isogenic lines of the unicellular green algae Chlamydomonas reinhardtii with prolonged exposure to a rotifer predator. We confirm that growth in cell groups is heritable and characterized by a convex trade-off curve between reproduction and survival. Identical mutations evolve in all cell group isolates; these are linked to survival and reducing associated cell costs. Overall, we show that just 500 generations of predator selection were sufficient to lead to a convex trade-off and incorporate evolved changes into the prey genome. |
format | Online Article Text |
id | pubmed-8270964 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-82709642021-07-23 The evolution of convex trade-offs enables the transition towards multicellularity Bernardes, Joana P. John, Uwe Woltermann, Noemi Valiadi, Martha Hermann, Ruben J. Becks, Lutz Nat Commun Article The evolutionary transition towards multicellular life often involves growth in groups of undifferentiated cells followed by differentiation into soma and germ-like cells. Theory predicts that germ soma differentiation is facilitated by a convex trade-off between survival and reproduction. However, this has never been tested and these transitions remain poorly understood at the ecological and genetic level. Here, we study the evolution of cell groups in ten isogenic lines of the unicellular green algae Chlamydomonas reinhardtii with prolonged exposure to a rotifer predator. We confirm that growth in cell groups is heritable and characterized by a convex trade-off curve between reproduction and survival. Identical mutations evolve in all cell group isolates; these are linked to survival and reducing associated cell costs. Overall, we show that just 500 generations of predator selection were sufficient to lead to a convex trade-off and incorporate evolved changes into the prey genome. Nature Publishing Group UK 2021-07-09 /pmc/articles/PMC8270964/ /pubmed/34244514 http://dx.doi.org/10.1038/s41467-021-24503-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Bernardes, Joana P. John, Uwe Woltermann, Noemi Valiadi, Martha Hermann, Ruben J. Becks, Lutz The evolution of convex trade-offs enables the transition towards multicellularity |
title | The evolution of convex trade-offs enables the transition towards multicellularity |
title_full | The evolution of convex trade-offs enables the transition towards multicellularity |
title_fullStr | The evolution of convex trade-offs enables the transition towards multicellularity |
title_full_unstemmed | The evolution of convex trade-offs enables the transition towards multicellularity |
title_short | The evolution of convex trade-offs enables the transition towards multicellularity |
title_sort | evolution of convex trade-offs enables the transition towards multicellularity |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270964/ https://www.ncbi.nlm.nih.gov/pubmed/34244514 http://dx.doi.org/10.1038/s41467-021-24503-z |
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