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Exchange catalysis by tapasin exploits conserved and allele-specific features of MHC-I molecules

The repertoire of peptides presented by major histocompatibility complex class I (MHC-I) molecules on the cell surface is tailored by the ER-resident peptide loading complex (PLC), which contains the exchange catalyst tapasin. Tapasin stabilizes MHC-I molecules and promotes the formation of stable p...

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Detalles Bibliográficos
Autores principales:	Lan, Huan, Abualrous, Esam T., Sticht, Jana, Fernandez, Laura Maria Arroyo, Werk, Tamina, Weise, Christoph, Ballaschk, Martin, Schmieder, Peter, Loll, Bernhard, Freund, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271027/ https://www.ncbi.nlm.nih.gov/pubmed/34244493 http://dx.doi.org/10.1038/s41467-021-24401-4

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