Cargando…

Metabolic maturation of differentiating cardiosphere-derived cells

Cardiosphere-derived cells (CDCs) can be expanded in vitro and induced to differentiate along the cardiac lineage. To recapitulate the phenotype of an adult cardiomyocyte, differentiating progenitors need to upregulate mitochondrial glucose and fatty acid oxidation. Here we cultured and differentiat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pakzad, Khadijeh Kathy, Tan, Jun Jie, Anderson, Stephanie, Board, Mary, Clarke, Kieran, Carr, Carolyn A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271094/ https://www.ncbi.nlm.nih.gov/pubmed/34118565 http://dx.doi.org/10.1016/j.scr.2021.102422

Ejemplares similares

Cardiosphere-Derived Cells Improve Function in the Infarcted Rat Heart for at Least 16 Weeks – an MRI Study
por: Carr, Carolyn A., et al.
Publicado: (2011)

Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors
por: Tan, Suat Cheng, et al.
Publicado: (2011)

Human Cardiosphere-Derived Cells from Patients with Chronic Ischaemic Heart Disease Can Be Routinely Expanded from Atrial but Not Epicardial Ventricular Biopsies
por: Chan, Helen H. L., et al.
Publicado: (2012)

Erratum to: Human Cardiosphere-Derived Cells from Patients with Chronic Ischaemic Heart Disease Can Be Routinely Expanded from Atrial but Not Epicardial Ventricular Biopsies
por: Chan, Helen H. L., et al.
Publicado: (2012)

2194: Effects of anoxia on viability and differentiation of human cardiosphere-derived cells
por: Khanjyan, Michael, et al.
Publicado: (2018)

Cardiosphere-Derived Cells Demonstrate Metabolic Flexibility That Is Influenced by Adhesion Status
por: Afzal, Junaid, et al.
Publicado: (2017)

THY-1 Receptor Expression Differentiates Cardiosphere-Derived Cells with Divergent Cardiogenic Differentiation Potential
por: Gago-Lopez, Nuria, et al.
Publicado: (2014)

Cell Shape and Cardiosphere Differentiation: A Revelation by Proteomic Profiling
por: Kawaguchi, Nanako, et al.
Publicado: (2013)

Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis
por: Redgrave, Rachael E., et al.
Publicado: (2017)

Cardiac regenerative potential of cardiosphere-derived cells from adult dog hearts
por: Hensley, Michael Taylor, et al.
Publicado: (2015)

Cardiosphere-derived cells do not improve cardiac function in rats with cardiac failure
por: Kasai-Brunswick, Taís Hanae, et al.
Publicado: (2017)

Therapeutic benefits of intravenous cardiosphere-derived cell therapy in rats with pulmonary hypertension
por: Middleton, Ryan C., et al.
Publicado: (2017)

Normal versus Pathological Cardiac Fibroblast-Derived Extracellular Matrix Differentially Modulates Cardiosphere-Derived Cell Paracrine Properties and Commitment
por: Pagano, Francesca, et al.
Publicado: (2017)

Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing
por: Kogan, Palgit-S., et al.
Publicado: (2022)

Exosomes Secreted by Normoxic and Hypoxic Cardiosphere-derived Cells Have Anti-apoptotic Effect
por: Namazi, Helia, et al.
Publicado: (2018)

Intracoronary allogeneic cardiosphere‐derived stem cells are safe for use in dogs with dilated cardiomyopathy
por: Hensley, Michael Taylor, et al.
Publicado: (2017)

Biodistribution of unmodified cardiosphere‐derived cell extracellular vesicles using single RNA tracing
por: Ciullo, Alessandra, et al.
Publicado: (2022)

Metabolic flux analyses to assess the differentiation of adult cardiac progenitors after fatty acid supplementation
por: Malandraki-Miller, Sophia, et al.
Publicado: (2019)

Microscale Generation of Cardiospheres Promotes Robust Enrichment of Cardiomyocytes Derived from Human Pluripotent Stem Cells
por: Nguyen, Doan C., et al.
Publicado: (2014)

Mechanically induced pyroptosis enhances cardiosphere oxidative stress resistance and metabolism for myocardial infarction therapy
por: Wang, Yingwei, et al.
Publicado: (2023)

Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species
por: Board, Mary, et al.
Publicado: (2017)

Automated Segmentation of Fluorescence Microscopy Images for 3D Cell Detection in human-derived Cardiospheres
por: Salvi, Massimo, et al.
Publicado: (2019)

The epicardial delivery of cardiosphere derived cells or their extracellular vesicles is safe but of limited value in experimental infarction
por: Crisóstomo, Verónica, et al.
Publicado: (2021)

Isoproterenol pre-treatment improve the therapeutic efficacy of cardiosphere-derived cells transplantation for myocardial infarction
por: Duan, Xiaoying, et al.
Publicado: (2023)

Notch pathway activation enhances cardiosphere in vitro expansion
por: Secco, Ilaria, et al.
Publicado: (2018)

Human Cardiospheres as a Source of Multipotent Stem and Progenitor Cells
por: Barile, Lucio, et al.
Publicado: (2013)

Cardiosphere-Derived Cells Reverse Heart Failure With Preserved Ejection Fraction in Rats by Decreasing Fibrosis and Inflammation
por: Gallet, Romain, et al.
Publicado: (2016)

Intrapericardial Delivery of Cardiosphere-Derived Cells: An Immunological Study in a Clinically Relevant Large Animal Model
por: Blázquez, Rebeca, et al.
Publicado: (2016)

Β-blockers treatment of cardiac surgery patients enhances isolation and improves phenotype of cardiosphere-derived cells
por: Chimenti, Isotta, et al.
Publicado: (2016)

The Immunomodulatory Signature of Extracellular Vesicles From Cardiosphere-Derived Cells: A Proteomic and miRNA Profiling
por: López, Esther, et al.
Publicado: (2020)

Heart-targeting exosomes from human cardiosphere-derived cells improve the therapeutic effect on cardiac hypertrophy
por: Mao, Liang, et al.
Publicado: (2022)

Cardiospheres and tissue engineering for myocardial regeneration: potential for clinical application
por: Gaetani, Roberto, et al.
Publicado: (2010)

Serum and supplement optimization for EU GMP-compliance in cardiospheres cell culture
por: Chimenti, Isotta, et al.
Publicado: (2014)

Heart to heart: grafting cardiosphere-derived cells augments cardiac self-repair by both myocytes and stem cells
por: Palacios, Jose A, et al.
Publicado: (2013)

Metformin promotes the survival of transplanted cardiosphere-derived cells thereby enhancing their therapeutic effect against myocardial infarction
por: Yue, Rongchuan, et al.
Publicado: (2017)

Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor
por: Dutton, Luke C., et al.
Publicado: (2018)

Effect of cardiosphere-derived cells on segmental myocardial function after myocardial infarction: ALLSTAR randomised clinical trial
por: Ostovaneh, Mohammad R, et al.
Publicado: (2021)

Therapeutic effects of CXCR4(+) subpopulation of transgene‐free induced cardiosphere‐derived cells on experimental myocardial infarction
por: Xu, Jianyong, et al.
Publicado: (2021)

Mechanistic and therapeutic distinctions between cardiosphere-derived cell and mesenchymal stem cell extracellular vesicle non-coding RNA
por: Walravens, Ann-Sophie, et al.
Publicado: (2021)

Validation of the Cardiosphere Method to Culture Cardiac Progenitor Cells from Myocardial Tissue
por: Davis, Darryl R., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_5rfr5tpiu945hap12534rmb60q