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Inhibition of Hepatitis B Virus by AAV8-Derived CRISPR/SaCas9 Expressed From Liver-Specific Promoters

Curative therapies for chronic hepatitis B virus (HBV) infection remain a distant goal, and the persistence of stable covalently closed circular DNA (cccDNA) during HBV replication is a key barrier that is hard to break through using the drugs currently approved for HBV treatment. Due to the accurac...

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Detalles Bibliográficos
Autores principales:	Yan, Kun, Feng, Jiangpeng, Liu, Xing, Wang, Hongyun, Li, Qiaohong, Li, Jiali, Xu, Tianmo, Sajid, Muhammad, Ullah, Hafiz, Zhou, Li, Zhou, Limin, Chen, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271097/ https://www.ncbi.nlm.nih.gov/pubmed/34254007 http://dx.doi.org/10.3389/fmicb.2021.665184

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