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Boosted activity by engineering the enzyme microenvironment in cascade reaction: A molecular understanding

Engineering of enzyme microenvironment can surprisingly boost the apparent activity. However, the underlying regulation mechanism is not well-studied at a molecular level so far. Here, we present a modulation of two model enzymes of cytochrome c (Cty C) and (d)-amino acid oxidase (DAAO) with opposit...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhang, Haiyang, Yin, Deping, Xu, Xiao, Tan, Tianwei, Lv, Yongqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271104/
https://www.ncbi.nlm.nih.gov/pubmed/34278014
http://dx.doi.org/10.1016/j.synbio.2021.06.004