Standardization of assay representation in the Ontology for Biomedical Investigations

The Ontology for Biomedical Investigations (OBI) underwent a focused review of assay term annotations, logic and hierarchy with a goal to improve and standardize these terms. As a result, inconsistencies in W3C Web Ontology Language (OWL) expressions were identified and corrected, and additionally,...

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Detalles Bibliográficos
Autores principales: Vita, Randi, Zheng, Jie, Jackson, Rebecca, Dooley, Damion, Overton, James A, Miller, Mark A, Berrios, Daniel C, Scheuermann, Richard H, He, Yongqun, McGinty, Hande Küçük, Brochhausen, Mathias, Lin, Aisyah Yu, Jain, Sagar B, Chibucos, Marcus C, Judkins, John, Giglio, Michelle G, Feng, Irene Y, Burns, Gully, Brush, Matthew H, Peters, Bjoern, Stoeckert Jr, Christian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271124/
https://www.ncbi.nlm.nih.gov/pubmed/34244718
http://dx.doi.org/10.1093/database/baab040
Descripción
Sumario:The Ontology for Biomedical Investigations (OBI) underwent a focused review of assay term annotations, logic and hierarchy with a goal to improve and standardize these terms. As a result, inconsistencies in W3C Web Ontology Language (OWL) expressions were identified and corrected, and additionally, standardized design patterns and a formalized template to maintain them were developed. We describe here this informative and productive process to describe the specific benefits and obstacles for OBI and the universal lessons for similar projects.

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