NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells

Spermatogonial stem cells (SSCs) sustain spermatogenesis and fertility throughout adult male life. The conserved RNA-binding protein NANOS2 is essential for the maintenance of SSCs, but its targets and mechanisms of function are not fully understood. Here, we generated a fully functional epitope-tag...

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Detalles Bibliográficos
Autores principales: Codino, Azzurra, Turowski, Tomasz, van de Lagemaat, Louie N., Ivanova, Ivayla, Tavosanis, Andrea, Much, Christian, Auchynnikava, Tania, Vasiliauskaitė, Lina, Morgan, Marcos, Rappsilber, Juri, Allshire, Robin C., Kranc, Kamil R., Tollervey, David, O'Carroll, Dónal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271163/
https://www.ncbi.nlm.nih.gov/pubmed/34278268
http://dx.doi.org/10.1016/j.isci.2021.102762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271163/
https://www.ncbi.nlm.nih.gov/pubmed/34278268
http://dx.doi.org/10.1016/j.isci.2021.102762

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