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Thyroid Hormone Receptor Beta Inhibits PI3K-Akt-mTOR Signaling Axis in Anaplastic Thyroid Cancer via Genomic Mechanisms

Thyroid cancer is the most common endocrine malignancy, and the global incidence has increased rapidly over the past few decades. Anaplastic thyroid cancer (ATC) is highly aggressive, dedifferentiated, and patients have a median survival of fewer than 6 months. Oncogenic alterations in ATC include a...

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Detalles Bibliográficos
Autores principales: Davidson, Cole D, Bolf, Eric L, Gillis, Noelle E, Cozzens, Lauren M, Tomczak, Jennifer A, Carr, Frances E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271203/
https://www.ncbi.nlm.nih.gov/pubmed/34258492
http://dx.doi.org/10.1210/jendso/bvab102

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