Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in a dynamic response to acute kidney injury

Acute kidney injury (AKI), commonly caused by ischemia, sepsis, or nephrotoxic insult, is associated with increased mortality and a heightened risk of chronic kidney disease (CKD). AKI results in the dysfunction or death of proximal tubule cells (PTCs), triggering a poorly understood autologous cell...

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Detalles Bibliográficos
Autores principales: Gerhardt, Louisa M. S., Liu, Jing, Koppitch, Kari, Cippà, Pietro E., McMahon, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271768/
https://www.ncbi.nlm.nih.gov/pubmed/34183416
http://dx.doi.org/10.1073/pnas.2026684118

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