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Stimulus-Responsive Polymers Based on Polypeptoid Skeletons
Polypeptoids have attracted a lot of atteSDntion because of their unique structural characteristics and special properties. Polypeptoids have the same main chain structures to polypeptides, making them have low cytotoxicity and excellent biocompatibility. Polypeptoids can also respond to external en...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271857/ https://www.ncbi.nlm.nih.gov/pubmed/34202869 http://dx.doi.org/10.3390/polym13132089 |
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author | Fang, Rui Pi, Junwei Wei, Tiantian Ali, Amjad Guo, Li |
author_facet | Fang, Rui Pi, Junwei Wei, Tiantian Ali, Amjad Guo, Li |
author_sort | Fang, Rui |
collection | PubMed |
description | Polypeptoids have attracted a lot of atteSDntion because of their unique structural characteristics and special properties. Polypeptoids have the same main chain structures to polypeptides, making them have low cytotoxicity and excellent biocompatibility. Polypeptoids can also respond to external environmental changes by modifying the configurations of the side chains. The external stimuli can be heat, pH, ions, ultraviolet/visible light and active oxygen or their combinations. This review paper discussed the recent research progress in the field of stimulus-responsive polypeptoids, including the design of new stimulus-responsive polypeptoid structures, controlled actuation factors in response to external stimuli and the application of responsive polypeptoid biomaterials in various biomedical and biological nanotechnology, such as drug delivery, tissue engineering and biosensing. |
format | Online Article Text |
id | pubmed-8271857 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82718572021-07-11 Stimulus-Responsive Polymers Based on Polypeptoid Skeletons Fang, Rui Pi, Junwei Wei, Tiantian Ali, Amjad Guo, Li Polymers (Basel) Review Polypeptoids have attracted a lot of atteSDntion because of their unique structural characteristics and special properties. Polypeptoids have the same main chain structures to polypeptides, making them have low cytotoxicity and excellent biocompatibility. Polypeptoids can also respond to external environmental changes by modifying the configurations of the side chains. The external stimuli can be heat, pH, ions, ultraviolet/visible light and active oxygen or their combinations. This review paper discussed the recent research progress in the field of stimulus-responsive polypeptoids, including the design of new stimulus-responsive polypeptoid structures, controlled actuation factors in response to external stimuli and the application of responsive polypeptoid biomaterials in various biomedical and biological nanotechnology, such as drug delivery, tissue engineering and biosensing. MDPI 2021-06-24 /pmc/articles/PMC8271857/ /pubmed/34202869 http://dx.doi.org/10.3390/polym13132089 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Fang, Rui Pi, Junwei Wei, Tiantian Ali, Amjad Guo, Li Stimulus-Responsive Polymers Based on Polypeptoid Skeletons |
title | Stimulus-Responsive Polymers Based on Polypeptoid Skeletons |
title_full | Stimulus-Responsive Polymers Based on Polypeptoid Skeletons |
title_fullStr | Stimulus-Responsive Polymers Based on Polypeptoid Skeletons |
title_full_unstemmed | Stimulus-Responsive Polymers Based on Polypeptoid Skeletons |
title_short | Stimulus-Responsive Polymers Based on Polypeptoid Skeletons |
title_sort | stimulus-responsive polymers based on polypeptoid skeletons |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271857/ https://www.ncbi.nlm.nih.gov/pubmed/34202869 http://dx.doi.org/10.3390/polym13132089 |
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