Serological response in health care workers after a single dose of SARS-CoV-2 vaccine using six automated SARS-CoV-2 antibody assays

Spike (S)- and nucleocapsid (N)-specific serological assay responses were determined before and/or after first dose SARS-CoV-2 vaccination in 22 individuals. S-specific assays quantified antibodies after vaccination with significant higher levels in participants with a previous infection. Be cautiou...

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Detalles Bibliográficos
Autores principales: Cuykx, Matthias, Mortelé, Olivier, Jansens, Hilde, Schouwers, Sofie, Meskal, Anissa, Hoffbauer, Ilse, Peeters, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272050/
https://www.ncbi.nlm.nih.gov/pubmed/34332306
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115486
Descripción
Sumario:Spike (S)- and nucleocapsid (N)-specific serological assay responses were determined before and/or after first dose SARS-CoV-2 vaccination in 22 individuals. S-specific assays quantified antibodies after vaccination with significant higher levels in participants with a previous infection. Be cautious combining N-/S-specific assay results, potentially differentiating post-infection/vaccination immunization as assay-specific N-antibody waning was observed.

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