Serological response in health care workers after a single dose of SARS-CoV-2 vaccine using six automated SARS-CoV-2 antibody assays

Spike (S)- and nucleocapsid (N)-specific serological assay responses were determined before and/or after first dose SARS-CoV-2 vaccination in 22 individuals. S-specific assays quantified antibodies after vaccination with significant higher levels in participants with a previous infection. Be cautiou...

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Autores principales: Cuykx, Matthias, Mortelé, Olivier, Jansens, Hilde, Schouwers, Sofie, Meskal, Anissa, Hoffbauer, Ilse, Peeters, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272050/
https://www.ncbi.nlm.nih.gov/pubmed/34332306
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115486
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author Cuykx, Matthias
Mortelé, Olivier
Jansens, Hilde
Schouwers, Sofie
Meskal, Anissa
Hoffbauer, Ilse
Peeters, Bart
author_facet Cuykx, Matthias
Mortelé, Olivier
Jansens, Hilde
Schouwers, Sofie
Meskal, Anissa
Hoffbauer, Ilse
Peeters, Bart
author_sort Cuykx, Matthias
collection PubMed
description Spike (S)- and nucleocapsid (N)-specific serological assay responses were determined before and/or after first dose SARS-CoV-2 vaccination in 22 individuals. S-specific assays quantified antibodies after vaccination with significant higher levels in participants with a previous infection. Be cautious combining N-/S-specific assay results, potentially differentiating post-infection/vaccination immunization as assay-specific N-antibody waning was observed.
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spelling pubmed-82720502021-07-20 Serological response in health care workers after a single dose of SARS-CoV-2 vaccine using six automated SARS-CoV-2 antibody assays Cuykx, Matthias Mortelé, Olivier Jansens, Hilde Schouwers, Sofie Meskal, Anissa Hoffbauer, Ilse Peeters, Bart Diagn Microbiol Infect Dis Article Spike (S)- and nucleocapsid (N)-specific serological assay responses were determined before and/or after first dose SARS-CoV-2 vaccination in 22 individuals. S-specific assays quantified antibodies after vaccination with significant higher levels in participants with a previous infection. Be cautious combining N-/S-specific assay results, potentially differentiating post-infection/vaccination immunization as assay-specific N-antibody waning was observed. Elsevier Inc. 2021-10 2021-07-10 /pmc/articles/PMC8272050/ /pubmed/34332306 http://dx.doi.org/10.1016/j.diagmicrobio.2021.115486 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Cuykx, Matthias
Mortelé, Olivier
Jansens, Hilde
Schouwers, Sofie
Meskal, Anissa
Hoffbauer, Ilse
Peeters, Bart
Serological response in health care workers after a single dose of SARS-CoV-2 vaccine using six automated SARS-CoV-2 antibody assays
title Serological response in health care workers after a single dose of SARS-CoV-2 vaccine using six automated SARS-CoV-2 antibody assays
title_full Serological response in health care workers after a single dose of SARS-CoV-2 vaccine using six automated SARS-CoV-2 antibody assays
title_fullStr Serological response in health care workers after a single dose of SARS-CoV-2 vaccine using six automated SARS-CoV-2 antibody assays
title_full_unstemmed Serological response in health care workers after a single dose of SARS-CoV-2 vaccine using six automated SARS-CoV-2 antibody assays
title_short Serological response in health care workers after a single dose of SARS-CoV-2 vaccine using six automated SARS-CoV-2 antibody assays
title_sort serological response in health care workers after a single dose of sars-cov-2 vaccine using six automated sars-cov-2 antibody assays
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272050/
https://www.ncbi.nlm.nih.gov/pubmed/34332306
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115486
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