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Optical Glucose Sensor Using Pressure Sensitive Paint
A glucose sensor is used as an essential tool for diagnosing and treating diabetic patients and controlling processes during cell culture. Since the development of an electrochemical-based glucose sensor, an optical glucose sensor has been devised to overcome its shortcomings, but this also poses a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272239/ https://www.ncbi.nlm.nih.gov/pubmed/34208846 http://dx.doi.org/10.3390/s21134474 |
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author | Park, Jongwon |
author_facet | Park, Jongwon |
author_sort | Park, Jongwon |
collection | PubMed |
description | A glucose sensor is used as an essential tool for diagnosing and treating diabetic patients and controlling processes during cell culture. Since the development of an electrochemical-based glucose sensor, an optical glucose sensor has been devised to overcome its shortcomings, but this also poses a problem because it requires a complicated manufacturing process. This study aimed to develop an optical glucose sensor film that could be fabricated with a simple process using commercial pressure sensitive paints. The sensor manufacturing technology developed in this work could simplify the complex production process of the existing electrochemical or optical glucose sensors. In addition, a photometric method for glucose concentration analysis was developed using the color image of the sensor. By developing this sensor and analysis technology, the basis for glucose measurement was established that enables two-dimensional, online, and continuous measurement. The proposed sensor showed good linearity at 0–4 mM glucose in an aqueous sample solution, its limit of detection was 0.37 mM, and the response time was 2 min. |
format | Online Article Text |
id | pubmed-8272239 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82722392021-07-11 Optical Glucose Sensor Using Pressure Sensitive Paint Park, Jongwon Sensors (Basel) Communication A glucose sensor is used as an essential tool for diagnosing and treating diabetic patients and controlling processes during cell culture. Since the development of an electrochemical-based glucose sensor, an optical glucose sensor has been devised to overcome its shortcomings, but this also poses a problem because it requires a complicated manufacturing process. This study aimed to develop an optical glucose sensor film that could be fabricated with a simple process using commercial pressure sensitive paints. The sensor manufacturing technology developed in this work could simplify the complex production process of the existing electrochemical or optical glucose sensors. In addition, a photometric method for glucose concentration analysis was developed using the color image of the sensor. By developing this sensor and analysis technology, the basis for glucose measurement was established that enables two-dimensional, online, and continuous measurement. The proposed sensor showed good linearity at 0–4 mM glucose in an aqueous sample solution, its limit of detection was 0.37 mM, and the response time was 2 min. MDPI 2021-06-30 /pmc/articles/PMC8272239/ /pubmed/34208846 http://dx.doi.org/10.3390/s21134474 Text en © 2021 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Park, Jongwon Optical Glucose Sensor Using Pressure Sensitive Paint |
title | Optical Glucose Sensor Using Pressure Sensitive Paint |
title_full | Optical Glucose Sensor Using Pressure Sensitive Paint |
title_fullStr | Optical Glucose Sensor Using Pressure Sensitive Paint |
title_full_unstemmed | Optical Glucose Sensor Using Pressure Sensitive Paint |
title_short | Optical Glucose Sensor Using Pressure Sensitive Paint |
title_sort | optical glucose sensor using pressure sensitive paint |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272239/ https://www.ncbi.nlm.nih.gov/pubmed/34208846 http://dx.doi.org/10.3390/s21134474 |
work_keys_str_mv | AT parkjongwon opticalglucosesensorusingpressuresensitivepaint |