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YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m(6)A modification to activate NF-κB and promote the malignant progression of glioma

BACKGROUND: The prognosis for diffuse gliomas is very poor and the mechanism underlying their malignant progression remains unclear. Here, we aimed to elucidate the role and mechanism of the RNA N6,2′-O-dimethyladenosine (m(6)A) reader, YTH N6-methyladenosine RNA binding protein 2 (YTHDF2), in regul...

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Detalles Bibliográficos
Autores principales:	Chai, Rui-Chao, Chang, Yu-Zhou, Chang, Xin, Pang, Bo, An, Song Yuan, Zhang, Ke-Nan, Chang, Yuan-Hao, Jiang, Tao, Wang, Yong-Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272379/ https://www.ncbi.nlm.nih.gov/pubmed/34246306 http://dx.doi.org/10.1186/s13045-021-01124-z

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