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Recent research on expiratory particles in respiratory viral infection and control strategies: A review
The global spread of coronavirus disease 2019 poses a significant threat to human health. In this study, recent research on the characteristics of expiratory particles and flow is reviewed, with a special focus on different respiratory activities, to provide guidance for reducing the viral infection...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272400/ https://www.ncbi.nlm.nih.gov/pubmed/34306994 http://dx.doi.org/10.1016/j.scs.2021.103106 |
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author | Bu, Yunchen Ooka, Ryozo Kikumoto, Hideki Oh, Wonseok |
author_facet | Bu, Yunchen Ooka, Ryozo Kikumoto, Hideki Oh, Wonseok |
author_sort | Bu, Yunchen |
collection | PubMed |
description | The global spread of coronavirus disease 2019 poses a significant threat to human health. In this study, recent research on the characteristics of expiratory particles and flow is reviewed, with a special focus on different respiratory activities, to provide guidance for reducing the viral infection risk in the built environment. Furthermore, environmental influence on particle evaporation, dispersion, and virus viability after exhalation and the current methods for infection risk assessment are reviewed. Finally, we summarize promising control strategies against infectious expiratory particles. The results show that airborne transmission is a significant viral transmission route, both in short and long ranges, from infected individuals. Relative humidity affects the evaporation and trajectories of middle-sized droplets most, and temperature accelerates the inactivation of SARS-CoV-2 both on surfaces and in aerosols. Future research is needed to improve infection risk models to better predict the infection potential of different transmission routes. Moreover, further quantitative studies on the expiratory flow features after wearing a mask are needed. Systematic investigations and the design of advanced air distribution methods, portable air cleaners, and ultraviolet germicidal irradiation systems, which have shown high efficacy in removing contaminants, are required to better control indoor viral infection. |
format | Online Article Text |
id | pubmed-8272400 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82724002021-07-20 Recent research on expiratory particles in respiratory viral infection and control strategies: A review Bu, Yunchen Ooka, Ryozo Kikumoto, Hideki Oh, Wonseok Sustain Cities Soc Article The global spread of coronavirus disease 2019 poses a significant threat to human health. In this study, recent research on the characteristics of expiratory particles and flow is reviewed, with a special focus on different respiratory activities, to provide guidance for reducing the viral infection risk in the built environment. Furthermore, environmental influence on particle evaporation, dispersion, and virus viability after exhalation and the current methods for infection risk assessment are reviewed. Finally, we summarize promising control strategies against infectious expiratory particles. The results show that airborne transmission is a significant viral transmission route, both in short and long ranges, from infected individuals. Relative humidity affects the evaporation and trajectories of middle-sized droplets most, and temperature accelerates the inactivation of SARS-CoV-2 both on surfaces and in aerosols. Future research is needed to improve infection risk models to better predict the infection potential of different transmission routes. Moreover, further quantitative studies on the expiratory flow features after wearing a mask are needed. Systematic investigations and the design of advanced air distribution methods, portable air cleaners, and ultraviolet germicidal irradiation systems, which have shown high efficacy in removing contaminants, are required to better control indoor viral infection. Elsevier Ltd. 2021-10 2021-06-18 /pmc/articles/PMC8272400/ /pubmed/34306994 http://dx.doi.org/10.1016/j.scs.2021.103106 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Bu, Yunchen Ooka, Ryozo Kikumoto, Hideki Oh, Wonseok Recent research on expiratory particles in respiratory viral infection and control strategies: A review |
title | Recent research on expiratory particles in respiratory viral infection and control strategies: A review |
title_full | Recent research on expiratory particles in respiratory viral infection and control strategies: A review |
title_fullStr | Recent research on expiratory particles in respiratory viral infection and control strategies: A review |
title_full_unstemmed | Recent research on expiratory particles in respiratory viral infection and control strategies: A review |
title_short | Recent research on expiratory particles in respiratory viral infection and control strategies: A review |
title_sort | recent research on expiratory particles in respiratory viral infection and control strategies: a review |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272400/ https://www.ncbi.nlm.nih.gov/pubmed/34306994 http://dx.doi.org/10.1016/j.scs.2021.103106 |
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