Cargando…

Systematic Analysis of the Oncogenic Role of WDR62 in Human Tumors

BACKGROUND: Emerging studies support the oncogenic role of WD repeat domain 62 (WDR62) in few tumors, while no pan-cancer analysis is available. In this study, we analyzed systematically the oncogenic role of WDR62 across a series of human tumors based on bioinformatic data mining. METHODS: The expr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bu, Yulan, Zhang, Lihua, Ma, Xiaolin, Wang, Rui, Zhang, Xuecheng, Li, Jiaqiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272457/ https://www.ncbi.nlm.nih.gov/pubmed/34306258 http://dx.doi.org/10.1155/2021/9940274

Ejemplares similares

Pathophysiological Significance of WDR62 and JNK Signaling in Human Diseases
por: Zhi, Yiqiang, et al.
Publicado: (2021)

Overexpression of WDR62 is associated with centrosome amplification in human ovarian cancer
por: Zhang, Yu, et al.
Publicado: (2013)

Docking interactions of the JNK scaffold protein WDR62
por: Cohen-Katsenelson, Ksenya, et al.
Publicado: (2011)

WDR62 variants contribute to congenital heart disease by inhibiting cardiomyocyte proliferation
por: Hao, Lili, et al.
Publicado: (2022)

WDR54 exerts oncogenic roles in T‐cell acute lymphoblastic leukemia
por: Li, Huan, et al.
Publicado: (2023)

Molecular evolution of WDR62, a gene that regulates neocorticogenesis
por: Pervaiz, Nashaiman, et al.
Publicado: (2016)

MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis
por: Xu, Dan, et al.
Publicado: (2018)

Exploring the oncogenic roles of LINC00857 in pan-cancer
por: Ren, Xiaomin, et al.
Publicado: (2022)

WDR62-deficiency Causes Autism-like Behaviors Independent of Microcephaly in Mice
por: Xu, Dan, et al.
Publicado: (2022)

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
por: Ho, Uda Y., et al.
Publicado: (2021)

WDR62 Regulates Early Neural and Glial Progenitor Specification of Human Pluripotent Stem Cells
por: Alshawaf, Abdullah J., et al.
Publicado: (2017)

Wdr62 is involved in female meiotic initiation via activating JNK signaling and associated with POI in humans
por: Zhou, Yang, et al.
Publicado: (2018)

Mutations in WDR62 gene in Pakistani families with autosomal recessive primary microcephaly
por: Kousar, Rizwana, et al.
Publicado: (2011)

The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus
por: Shohayeb, Belal, et al.
Publicado: (2020)

WDR62 localizes katanin at spindle poles to ensure synchronous chromosome segregation
por: Guerreiro, Amanda, et al.
Publicado: (2021)

Correction: Wdr62 is involved in female meiotic initiation via activating JNK signaling and associated with POI in humans
por: Zhou, Yang, et al.
Publicado: (2019)

Identification of WDR12 as a novel oncogene involved in hepatocellular carcinoma propagation
por: Yin, Yancun, et al.
Publicado: (2018)

Whole exome sequencing identifies recessive WDR62 mutations in severe brain malformations
por: Bilgüvar, Kaya, et al.
Publicado: (2010)

A novel single base pair duplication in WDR62 causes primary microcephaly
por: Rupp, Verena, et al.
Publicado: (2014)

Microcephaly-associated protein WDR62 shuttles from the Golgi apparatus to the spindle poles in human neural progenitors
por: Dell'Amico, Claudia, et al.
Publicado: (2023)

The role of WDR76 protein in human diseases
por: Yang, Jie, et al.
Publicado: (2021)

Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly
por: Sgourdou, Paraskevi, et al.
Publicado: (2017)

Pan-Cancer Analysis of the Roles and Driving Forces of RAB42
por: Zheng, Mingzhu, et al.
Publicado: (2022)

Microcephaly Disease Gene Wdr62 Regulates Mitotic Progression of Embryonic Neural Stem Cells and Brain Size
por: Chen, Jian-Fu, et al.
Publicado: (2014)

A novel WDR62 mutation causes primary microcephaly in a large consanguineous Saudi family
por: Naseer, Muhammad Imran, et al.
Publicado: (2017)

The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy
por: Liu, Xuezhao, et al.
Publicado: (2017)

WDR62 regulates spindle dynamics as an adaptor protein between TPX2/Aurora A and katanin
por: Huang, Junjie, et al.
Publicado: (2021)

WD repeat domain 62 (WDR62) promotes resistance of colorectal cancer to oxaliplatin through modulating mitogen-activated protein kinase (MAPK) signaling
por: Cai, Juanjuan, et al.
Publicado: (2022)

Structural insights into the activation of USP46 by WDR48 and WDR20
por: Zhu, Hanwen, et al.
Publicado: (2019)

WDR62 mediates TNFα-dependent JNK activation via TRAF2-MLK3 axis
por: Prinz, Elad, et al.
Publicado: (2018)

Novel compound heterozygous mutations in WDR62 gene leading to developmental delay and Primary Microcephaly in Saudi Family
por: Naseer, Muhammad Imran, et al.
Publicado: (2019)

Further Delineation of Phenotype and Genotype of Primary Microcephaly Syndrome with Cortical Malformations Associated with Mutations in the WDR62 Gene
por: Slezak, Ryszard, et al.
Publicado: (2021)

Identifying the oncogenic roles of FAP in human cancers based on systematic analysis
por: Ma, Chao, et al.
Publicado: (2023)

Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture
por: Yu, Timothy W., et al.
Publicado: (2010)

A novel non sense mutation in WDR62 causes autosomal recessive primary microcephaly: a case report
por: Cherkaoui Jaouad, Imane, et al.
Publicado: (2018)

Glial-Specific Functions of Microcephaly Protein WDR62 and Interaction with the Mitotic Kinase AURKA Are Essential for Drosophila Brain Growth
por: Lim, Nicholas R., et al.
Publicado: (2017)

Novel roles of METTL1/WDR4 in tumor via m(7)G methylation
por: Cheng, Wenli, et al.
Publicado: (2022)

Role of WDR5 in breast cancer prognosis
por: Stoeber, Regina
Publicado: (2019)

Integrative analysis of WDR12 as a potential prognostic and immunological biomarker in multiple human tumors
por: Eid, Refaat A., et al.
Publicado: (2023)

WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis: WDR38 interacts with RAB19 and GM130 in acrosome biogenesis
por: Gao, Qiujie, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_t75o66bv0ol8bmm978lrvu0tq0