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Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain
BACKGROUND: In order to impart immunity against SARS COV 2 in the community, the oil rich countries of the Gulf Cooperation Council (GCC) provided citizens and expatriates with free vaccination. Different types of vaccination brands were utilized for this purpose. The purpose of this study is to det...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272690/ https://www.ncbi.nlm.nih.gov/pubmed/34260903 http://dx.doi.org/10.1016/j.micpath.2021.105086 |
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author | Jahromi, Mohamed Al Sheikh, Mona Hmoud |
author_facet | Jahromi, Mohamed Al Sheikh, Mona Hmoud |
author_sort | Jahromi, Mohamed |
collection | PubMed |
description | BACKGROUND: In order to impart immunity against SARS COV 2 in the community, the oil rich countries of the Gulf Cooperation Council (GCC) provided citizens and expatriates with free vaccination. Different types of vaccination brands were utilized for this purpose. The purpose of this study is to determine the efficacy of the different types of vaccinations used. METHODS: This is an observational analytical case study of one Bahraini family who were vaccinated with 1st, 2nd or no dose. RESULTS: Out of 22 double dose recipients of SARS COV2 vaccine, 20 were infected. Those 20 were vaccinated against SARS COV 2 using Sinopharm, the rest (2) were in direct contact with the source but were vaccinated against SARS COV 2 using other type of vaccine. Out of 26 single dose recipients of Sinopharm vaccine, 23 were infected. The other three were not in direct contact with the infected source. Social gathering has been the main source of transmission. The infection has been mild with headache, chest pain. From 20 cases with double dose vaccinations only one had a lung infection and needed hospitalization. Out of 23 cases with single dose vaccinations 10 were hospitalized due to lung infections. All family members who were not vaccinated were infected, three were hospitalized one of which was deceased due to diabetes mellitus complications. CONLCUSION: Sinopharm provides partial protection against SARS COV 2 infection. That might be due to lack of its potential to detect recent variations in the protein structure of spike(S) protein of virus. |
format | Online Article Text |
id | pubmed-8272690 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82726902021-07-20 Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain Jahromi, Mohamed Al Sheikh, Mona Hmoud Microb Pathog Article BACKGROUND: In order to impart immunity against SARS COV 2 in the community, the oil rich countries of the Gulf Cooperation Council (GCC) provided citizens and expatriates with free vaccination. Different types of vaccination brands were utilized for this purpose. The purpose of this study is to determine the efficacy of the different types of vaccinations used. METHODS: This is an observational analytical case study of one Bahraini family who were vaccinated with 1st, 2nd or no dose. RESULTS: Out of 22 double dose recipients of SARS COV2 vaccine, 20 were infected. Those 20 were vaccinated against SARS COV 2 using Sinopharm, the rest (2) were in direct contact with the source but were vaccinated against SARS COV 2 using other type of vaccine. Out of 26 single dose recipients of Sinopharm vaccine, 23 were infected. The other three were not in direct contact with the infected source. Social gathering has been the main source of transmission. The infection has been mild with headache, chest pain. From 20 cases with double dose vaccinations only one had a lung infection and needed hospitalization. Out of 23 cases with single dose vaccinations 10 were hospitalized due to lung infections. All family members who were not vaccinated were infected, three were hospitalized one of which was deceased due to diabetes mellitus complications. CONLCUSION: Sinopharm provides partial protection against SARS COV 2 infection. That might be due to lack of its potential to detect recent variations in the protein structure of spike(S) protein of virus. Published by Elsevier Ltd. 2021-09 2021-07-11 /pmc/articles/PMC8272690/ /pubmed/34260903 http://dx.doi.org/10.1016/j.micpath.2021.105086 Text en © 2021 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Jahromi, Mohamed Al Sheikh, Mona Hmoud Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain |
title | Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain |
title_full | Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain |
title_fullStr | Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain |
title_full_unstemmed | Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain |
title_short | Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain |
title_sort | partial protection of sinopharm vaccine against sars cov2 during recent outbreak in bahrain |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272690/ https://www.ncbi.nlm.nih.gov/pubmed/34260903 http://dx.doi.org/10.1016/j.micpath.2021.105086 |
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