Cargando…

Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain

BACKGROUND: In order to impart immunity against SARS COV 2 in the community, the oil rich countries of the Gulf Cooperation Council (GCC) provided citizens and expatriates with free vaccination. Different types of vaccination brands were utilized for this purpose. The purpose of this study is to det...

Descripción completa

Detalles Bibliográficos
Autores principales: Jahromi, Mohamed, Al Sheikh, Mona Hmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272690/
https://www.ncbi.nlm.nih.gov/pubmed/34260903
http://dx.doi.org/10.1016/j.micpath.2021.105086
_version_ 1783721264237510656
author Jahromi, Mohamed
Al Sheikh, Mona Hmoud
author_facet Jahromi, Mohamed
Al Sheikh, Mona Hmoud
author_sort Jahromi, Mohamed
collection PubMed
description BACKGROUND: In order to impart immunity against SARS COV 2 in the community, the oil rich countries of the Gulf Cooperation Council (GCC) provided citizens and expatriates with free vaccination. Different types of vaccination brands were utilized for this purpose. The purpose of this study is to determine the efficacy of the different types of vaccinations used. METHODS: This is an observational analytical case study of one Bahraini family who were vaccinated with 1st, 2nd or no dose. RESULTS: Out of 22 double dose recipients of SARS COV2 vaccine, 20 were infected. Those 20 were vaccinated against SARS COV 2 using Sinopharm, the rest (2) were in direct contact with the source but were vaccinated against SARS COV 2 using other type of vaccine. Out of 26 single dose recipients of Sinopharm vaccine, 23 were infected. The other three were not in direct contact with the infected source. Social gathering has been the main source of transmission. The infection has been mild with headache, chest pain. From 20 cases with double dose vaccinations only one had a lung infection and needed hospitalization. Out of 23 cases with single dose vaccinations 10 were hospitalized due to lung infections. All family members who were not vaccinated were infected, three were hospitalized one of which was deceased due to diabetes mellitus complications. CONLCUSION: Sinopharm provides partial protection against SARS COV 2 infection. That might be due to lack of its potential to detect recent variations in the protein structure of spike(S) protein of virus.
format Online
Article
Text
id pubmed-8272690
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Published by Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-82726902021-07-20 Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain Jahromi, Mohamed Al Sheikh, Mona Hmoud Microb Pathog Article BACKGROUND: In order to impart immunity against SARS COV 2 in the community, the oil rich countries of the Gulf Cooperation Council (GCC) provided citizens and expatriates with free vaccination. Different types of vaccination brands were utilized for this purpose. The purpose of this study is to determine the efficacy of the different types of vaccinations used. METHODS: This is an observational analytical case study of one Bahraini family who were vaccinated with 1st, 2nd or no dose. RESULTS: Out of 22 double dose recipients of SARS COV2 vaccine, 20 were infected. Those 20 were vaccinated against SARS COV 2 using Sinopharm, the rest (2) were in direct contact with the source but were vaccinated against SARS COV 2 using other type of vaccine. Out of 26 single dose recipients of Sinopharm vaccine, 23 were infected. The other three were not in direct contact with the infected source. Social gathering has been the main source of transmission. The infection has been mild with headache, chest pain. From 20 cases with double dose vaccinations only one had a lung infection and needed hospitalization. Out of 23 cases with single dose vaccinations 10 were hospitalized due to lung infections. All family members who were not vaccinated were infected, three were hospitalized one of which was deceased due to diabetes mellitus complications. CONLCUSION: Sinopharm provides partial protection against SARS COV 2 infection. That might be due to lack of its potential to detect recent variations in the protein structure of spike(S) protein of virus. Published by Elsevier Ltd. 2021-09 2021-07-11 /pmc/articles/PMC8272690/ /pubmed/34260903 http://dx.doi.org/10.1016/j.micpath.2021.105086 Text en © 2021 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Jahromi, Mohamed
Al Sheikh, Mona Hmoud
Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain
title Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain
title_full Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain
title_fullStr Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain
title_full_unstemmed Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain
title_short Partial protection of Sinopharm vaccine against SARS COV2 during recent outbreak in Bahrain
title_sort partial protection of sinopharm vaccine against sars cov2 during recent outbreak in bahrain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272690/
https://www.ncbi.nlm.nih.gov/pubmed/34260903
http://dx.doi.org/10.1016/j.micpath.2021.105086
work_keys_str_mv AT jahromimohamed partialprotectionofsinopharmvaccineagainstsarscov2duringrecentoutbreakinbahrain
AT alsheikhmonahmoud partialprotectionofsinopharmvaccineagainstsarscov2duringrecentoutbreakinbahrain