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Blood Clotting and the Pathogenesis of Types I and II Hereditary Angioedema

The plasma contact system is the initiator of the intrinsic pathway of coagulation and the main producer of the inflammatory peptide bradykinin. When plasma is exposed to a negatively charged surface the two enzymes factor XII (FXII) and plasma prekallikrein (PK) bind to the surface alongside the co...

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Detalles Bibliográficos
Autores principales: de Maat, Steven, Joseph, Kusumam, Maas, Coen, Kaplan, Allen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272707/
https://www.ncbi.nlm.nih.gov/pubmed/33956309
http://dx.doi.org/10.1007/s12016-021-08837-6