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COVID-19 vaccines
COVID-19 is a pandemic of unprecedented proportions in recent human history. Less than 18 months since the onset of the pandemic, there are close to two hundred million confirmed cases and four million deaths worldwide. There have also been massive efforts geared towards finding safe and effective v...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272971/ https://www.ncbi.nlm.nih.gov/pubmed/34330017 http://dx.doi.org/10.1016/j.coi.2021.07.003 |
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author | Ndwandwe, Duduzile Wiysonge, Charles S |
author_facet | Ndwandwe, Duduzile Wiysonge, Charles S |
author_sort | Ndwandwe, Duduzile |
collection | PubMed |
description | COVID-19 is a pandemic of unprecedented proportions in recent human history. Less than 18 months since the onset of the pandemic, there are close to two hundred million confirmed cases and four million deaths worldwide. There have also been massive efforts geared towards finding safe and effective vaccines. By July 2021 there were 184 COVID-19 vaccine candidates in pre-clinical development, 105 in clinical development, and 18 vaccines approved for emergency use by at least one regulatory authority. These vaccines include whole virus live attenuated or inactivated, protein-based, viral vector, and nucleic acid vaccines. By mid-2021 three billion doses of COVID-19 vaccine have been administered around the world, mostly in high-income countries. COVID-19 vaccination provides hope for an end to the pandemic, if and only if there would be equal access and optimal uptake in all countries around the world. |
format | Online Article Text |
id | pubmed-8272971 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Author(s). Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82729712021-07-20 COVID-19 vaccines Ndwandwe, Duduzile Wiysonge, Charles S Curr Opin Immunol Article COVID-19 is a pandemic of unprecedented proportions in recent human history. Less than 18 months since the onset of the pandemic, there are close to two hundred million confirmed cases and four million deaths worldwide. There have also been massive efforts geared towards finding safe and effective vaccines. By July 2021 there were 184 COVID-19 vaccine candidates in pre-clinical development, 105 in clinical development, and 18 vaccines approved for emergency use by at least one regulatory authority. These vaccines include whole virus live attenuated or inactivated, protein-based, viral vector, and nucleic acid vaccines. By mid-2021 three billion doses of COVID-19 vaccine have been administered around the world, mostly in high-income countries. COVID-19 vaccination provides hope for an end to the pandemic, if and only if there would be equal access and optimal uptake in all countries around the world. The Author(s). Published by Elsevier Ltd. 2021-08 2021-07-12 /pmc/articles/PMC8272971/ /pubmed/34330017 http://dx.doi.org/10.1016/j.coi.2021.07.003 Text en © 2021 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Ndwandwe, Duduzile Wiysonge, Charles S COVID-19 vaccines |
title | COVID-19 vaccines |
title_full | COVID-19 vaccines |
title_fullStr | COVID-19 vaccines |
title_full_unstemmed | COVID-19 vaccines |
title_short | COVID-19 vaccines |
title_sort | covid-19 vaccines |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272971/ https://www.ncbi.nlm.nih.gov/pubmed/34330017 http://dx.doi.org/10.1016/j.coi.2021.07.003 |
work_keys_str_mv | AT ndwandweduduzile covid19vaccines AT wiysongecharless covid19vaccines |