Compliance with NPIs and possible deleterious effects on mitigation of an epidemic outbreak

The first attempt to control and mitigate an epidemic outbreak caused by a previously unknown virus occurs primarily via non-pharmaceutical interventions (NPIs). In case of the SARS-CoV-2 virus, which since the early days of 2020 caused the COVID-19 pandemic, NPIs aimed at reducing transmission-enab...

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Detalles Bibliográficos
Autores principales: Barbarossa, Maria Vittoria, Fuhrmann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273042/
https://www.ncbi.nlm.nih.gov/pubmed/34308001
http://dx.doi.org/10.1016/j.idm.2021.06.001
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author Barbarossa, Maria Vittoria
Fuhrmann, Jan
author_facet Barbarossa, Maria Vittoria
Fuhrmann, Jan
author_sort Barbarossa, Maria Vittoria
collection PubMed
description The first attempt to control and mitigate an epidemic outbreak caused by a previously unknown virus occurs primarily via non-pharmaceutical interventions (NPIs). In case of the SARS-CoV-2 virus, which since the early days of 2020 caused the COVID-19 pandemic, NPIs aimed at reducing transmission-enabling contacts between individuals. The effectiveness of contact reduction measures directly correlates with the number of individuals adhering to such measures. Here, we illustrate by means of a very simple compartmental model how partial noncompliance with NPIs can prevent these from stopping the spread of an epidemic.
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spelling pubmed-82730422021-07-20 Compliance with NPIs and possible deleterious effects on mitigation of an epidemic outbreak Barbarossa, Maria Vittoria Fuhrmann, Jan Infect Dis Model Original Research Article The first attempt to control and mitigate an epidemic outbreak caused by a previously unknown virus occurs primarily via non-pharmaceutical interventions (NPIs). In case of the SARS-CoV-2 virus, which since the early days of 2020 caused the COVID-19 pandemic, NPIs aimed at reducing transmission-enabling contacts between individuals. The effectiveness of contact reduction measures directly correlates with the number of individuals adhering to such measures. Here, we illustrate by means of a very simple compartmental model how partial noncompliance with NPIs can prevent these from stopping the spread of an epidemic. KeAi Publishing 2021-07-12 /pmc/articles/PMC8273042/ /pubmed/34308001 http://dx.doi.org/10.1016/j.idm.2021.06.001 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Research Article
Barbarossa, Maria Vittoria
Fuhrmann, Jan
Compliance with NPIs and possible deleterious effects on mitigation of an epidemic outbreak
title Compliance with NPIs and possible deleterious effects on mitigation of an epidemic outbreak
title_full Compliance with NPIs and possible deleterious effects on mitigation of an epidemic outbreak
title_fullStr Compliance with NPIs and possible deleterious effects on mitigation of an epidemic outbreak
title_full_unstemmed Compliance with NPIs and possible deleterious effects on mitigation of an epidemic outbreak
title_short Compliance with NPIs and possible deleterious effects on mitigation of an epidemic outbreak
title_sort compliance with npis and possible deleterious effects on mitigation of an epidemic outbreak
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273042/
https://www.ncbi.nlm.nih.gov/pubmed/34308001
http://dx.doi.org/10.1016/j.idm.2021.06.001
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