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Mutational Landscape of Pirin and Elucidation of the Impact of Most Detrimental Missense Variants That Accelerate the Breast Cancer Pathways: A Computational Modelling Study

Pirin (PIR) protein is highly conserved in both prokaryotic and eukaryotic organisms. Recently, it has been identified that PIR positively regulates breast cancer cell proliferation, xenograft tumor formation, and metastasis, through an enforced transition of G1/S phase of the cell cycle by upregula...

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Detalles Bibliográficos
Autores principales:	Suleman, Muhammad, Tahir ul Qamar, Muhammad, Saleem, Shoaib, Ahmad, Sajjad, Ali, Syed Shujait, Khan, Haji, Akbar, Fazal, Khan, Wajid, Alblihy, Adel, Alrumaihi, Faris, Waseem, Muhammad, Allemailem, Khaled S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273169/ https://www.ncbi.nlm.nih.gov/pubmed/34262943 http://dx.doi.org/10.3389/fmolb.2021.692835

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