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Crohn's Disease with Cutaneous Polyarteritis Nodosa in a Child: A Case Report
A 10-year-old boy presented with a 1-day history of multiple painful erythematous skin lesions on his upper and lower extremities. He was admitted to the Department of Pediatrics with persistent right lower abdominal pain and diarrhea. Punch biopsy of a skin lesion on his lower leg showed necrotizin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Dermatological Association; The Korean Society for Investigative Dermatology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273316/ https://www.ncbi.nlm.nih.gov/pubmed/34341639 http://dx.doi.org/10.5021/ad.2021.33.4.365 |
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author | Hong, Eun Hye Jung, Joon Woo Park, Eun Joo Kim, Kwang Joong Kim, Kwang Ho |
author_facet | Hong, Eun Hye Jung, Joon Woo Park, Eun Joo Kim, Kwang Joong Kim, Kwang Ho |
author_sort | Hong, Eun Hye |
collection | PubMed |
description | A 10-year-old boy presented with a 1-day history of multiple painful erythematous skin lesions on his upper and lower extremities. He was admitted to the Department of Pediatrics with persistent right lower abdominal pain and diarrhea. Punch biopsy of a skin lesion on his lower leg showed necrotizing granulomatous vasculitis with septal panniculitis consistent with polyarteritis nodosa, and our differential diagnosis included cutaneous manifestations of Croh's disease. Abdominal ultrasonography revealed distended colonic loops suggestive of inflammatory bowel disease. Upper and lower gastrointestinal endoscopy revealed lesions involving the duodenum, cecum, colon, and rectum. He developed multiple perianal fistulas during hospitalization. Additional laboratory tests revealed positive results for anti-saccharomyces cerevisiae and antinuclear antibodies. Based on his clinical presentation and laboratory findings, he was diagnosed with Crohn's disease associated with cutaneous polyarteritis nodosa. We report a rare case of a child who presented with cutaneous polyarteritis nodosa as an extraintestinal manifestation of Crohn's disease. |
format | Online Article Text |
id | pubmed-8273316 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Dermatological Association; The Korean Society for Investigative Dermatology |
record_format | MEDLINE/PubMed |
spelling | pubmed-82733162021-08-01 Crohn's Disease with Cutaneous Polyarteritis Nodosa in a Child: A Case Report Hong, Eun Hye Jung, Joon Woo Park, Eun Joo Kim, Kwang Joong Kim, Kwang Ho Ann Dermatol Case Report A 10-year-old boy presented with a 1-day history of multiple painful erythematous skin lesions on his upper and lower extremities. He was admitted to the Department of Pediatrics with persistent right lower abdominal pain and diarrhea. Punch biopsy of a skin lesion on his lower leg showed necrotizing granulomatous vasculitis with septal panniculitis consistent with polyarteritis nodosa, and our differential diagnosis included cutaneous manifestations of Croh's disease. Abdominal ultrasonography revealed distended colonic loops suggestive of inflammatory bowel disease. Upper and lower gastrointestinal endoscopy revealed lesions involving the duodenum, cecum, colon, and rectum. He developed multiple perianal fistulas during hospitalization. Additional laboratory tests revealed positive results for anti-saccharomyces cerevisiae and antinuclear antibodies. Based on his clinical presentation and laboratory findings, he was diagnosed with Crohn's disease associated with cutaneous polyarteritis nodosa. We report a rare case of a child who presented with cutaneous polyarteritis nodosa as an extraintestinal manifestation of Crohn's disease. The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2021-08 2021-07-01 /pmc/articles/PMC8273316/ /pubmed/34341639 http://dx.doi.org/10.5021/ad.2021.33.4.365 Text en Copyright © 2021 The Korean Dermatological Association and The Korean Society for Investigative Dermatology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Hong, Eun Hye Jung, Joon Woo Park, Eun Joo Kim, Kwang Joong Kim, Kwang Ho Crohn's Disease with Cutaneous Polyarteritis Nodosa in a Child: A Case Report |
title | Crohn's Disease with Cutaneous Polyarteritis Nodosa in a Child: A Case Report |
title_full | Crohn's Disease with Cutaneous Polyarteritis Nodosa in a Child: A Case Report |
title_fullStr | Crohn's Disease with Cutaneous Polyarteritis Nodosa in a Child: A Case Report |
title_full_unstemmed | Crohn's Disease with Cutaneous Polyarteritis Nodosa in a Child: A Case Report |
title_short | Crohn's Disease with Cutaneous Polyarteritis Nodosa in a Child: A Case Report |
title_sort | crohn's disease with cutaneous polyarteritis nodosa in a child: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273316/ https://www.ncbi.nlm.nih.gov/pubmed/34341639 http://dx.doi.org/10.5021/ad.2021.33.4.365 |
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