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Bioluminescent optogenetic (BL-OG) activation of neurons during mouse postnatal brain development

Bioluminescent optogenetics (BL-OG) allows activation of photosensory proteins, such as opsins, by either fiberoptics or by administering a luciferin. BL-OG thus confers both optogenetic and chemogenetic access within the same genetically targeted neuron. This bimodality offers a powerful approach f...

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Detalles Bibliográficos
Autores principales: Crespo, Emmanuel L., Prakash, Mansi, Bjorefeldt, Andreas, Medendorp, William E., Shaner, Nathan C., Lipscombe, Diane, Moore, Christopher I., Hochgeschwender, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273415/
https://www.ncbi.nlm.nih.gov/pubmed/34286295
http://dx.doi.org/10.1016/j.xpro.2021.100667