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Microglia replacement by bone marrow transplantation (Mr BMT) in the central nervous system of adult mice
Microglia are important immune cells in the central nervous system (CNS). Mutations in microglia may cause CNS disorders. Replacement of dysfunctional microglia with allogeneic wild-type microglia can correct the gene deficiency, thus treating the neurogenic diseases. However, traditional approaches...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273422/ https://www.ncbi.nlm.nih.gov/pubmed/34286294 http://dx.doi.org/10.1016/j.xpro.2021.100666 |