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Microglia replacement by bone marrow transplantation (Mr BMT) in the central nervous system of adult mice

Microglia are important immune cells in the central nervous system (CNS). Mutations in microglia may cause CNS disorders. Replacement of dysfunctional microglia with allogeneic wild-type microglia can correct the gene deficiency, thus treating the neurogenic diseases. However, traditional approaches...

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Detalles Bibliográficos
Autores principales: Xu, Zhen, Zhou, Xin, Peng, Bo, Rao, Yanxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273422/
https://www.ncbi.nlm.nih.gov/pubmed/34286294
http://dx.doi.org/10.1016/j.xpro.2021.100666