Anal adenocarcinoma: case report, literature review and comparative survival analysis

INTRODUCTION: Anal adenocarcinoma is a rare malignancy with a poor prognosis. METHODS: We present a case of rare anal adenocarcinoma in a patient with normal screening colonoscopy. Using the Surveillance, Epidemiology and End Result database between 2000 and 2016, we performed survival analysis amon...

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Detalles Bibliográficos
Autores principales: Tsay, Cynthia J, Pointer, Thomas, Chandler, Jocelyn B, Nagar, Anil B, Protiva, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Anorectal Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273449/
https://www.ncbi.nlm.nih.gov/pubmed/34244243
http://dx.doi.org/10.1136/bmjgast-2021-000661
Descripción
Sumario:INTRODUCTION: Anal adenocarcinoma is a rare malignancy with a poor prognosis. METHODS: We present a case of rare anal adenocarcinoma in a patient with normal screening colonoscopy. Using the Surveillance, Epidemiology and End Result database between 2000 and 2016, we performed survival analysis among individuals>20 years old comparing anal and rectal cancers. RESULTS: Survival analysis showed that anal adenocarcinoma is associated with worse outcomes compared with rectal adenocarcinoma and anal squamous cell carcinoma. DISCUSSION: This case and survival data illustrate the importance of prompt investigation of symptoms irrespective of colorectal cancer screening status with careful attention to examination of the anal area.

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