Anal adenocarcinoma: case report, literature review and comparative survival analysis

INTRODUCTION: Anal adenocarcinoma is a rare malignancy with a poor prognosis. METHODS: We present a case of rare anal adenocarcinoma in a patient with normal screening colonoscopy. Using the Surveillance, Epidemiology and End Result database between 2000 and 2016, we performed survival analysis amon...

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Autores principales: Tsay, Cynthia J, Pointer, Thomas, Chandler, Jocelyn B, Nagar, Anil B, Protiva, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Anorectal Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273449/
https://www.ncbi.nlm.nih.gov/pubmed/34244243
http://dx.doi.org/10.1136/bmjgast-2021-000661
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author Tsay, Cynthia J
Pointer, Thomas
Chandler, Jocelyn B
Nagar, Anil B
Protiva, Petr
author_facet Tsay, Cynthia J
Pointer, Thomas
Chandler, Jocelyn B
Nagar, Anil B
Protiva, Petr
author_sort Tsay, Cynthia J
collection PubMed
description INTRODUCTION: Anal adenocarcinoma is a rare malignancy with a poor prognosis. METHODS: We present a case of rare anal adenocarcinoma in a patient with normal screening colonoscopy. Using the Surveillance, Epidemiology and End Result database between 2000 and 2016, we performed survival analysis among individuals>20 years old comparing anal and rectal cancers. RESULTS: Survival analysis showed that anal adenocarcinoma is associated with worse outcomes compared with rectal adenocarcinoma and anal squamous cell carcinoma. DISCUSSION: This case and survival data illustrate the importance of prompt investigation of symptoms irrespective of colorectal cancer screening status with careful attention to examination of the anal area.
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spelling pubmed-82734492021-07-23 Anal adenocarcinoma: case report, literature review and comparative survival analysis Tsay, Cynthia J Pointer, Thomas Chandler, Jocelyn B Nagar, Anil B Protiva, Petr BMJ Open Gastroenterol Anorectal Disease INTRODUCTION: Anal adenocarcinoma is a rare malignancy with a poor prognosis. METHODS: We present a case of rare anal adenocarcinoma in a patient with normal screening colonoscopy. Using the Surveillance, Epidemiology and End Result database between 2000 and 2016, we performed survival analysis among individuals>20 years old comparing anal and rectal cancers. RESULTS: Survival analysis showed that anal adenocarcinoma is associated with worse outcomes compared with rectal adenocarcinoma and anal squamous cell carcinoma. DISCUSSION: This case and survival data illustrate the importance of prompt investigation of symptoms irrespective of colorectal cancer screening status with careful attention to examination of the anal area. BMJ Publishing Group 2021-07-09 /pmc/articles/PMC8273449/ /pubmed/34244243 http://dx.doi.org/10.1136/bmjgast-2021-000661 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Anorectal Disease
Tsay, Cynthia J
Pointer, Thomas
Chandler, Jocelyn B
Nagar, Anil B
Protiva, Petr
Anal adenocarcinoma: case report, literature review and comparative survival analysis
title Anal adenocarcinoma: case report, literature review and comparative survival analysis
title_full Anal adenocarcinoma: case report, literature review and comparative survival analysis
title_fullStr Anal adenocarcinoma: case report, literature review and comparative survival analysis
title_full_unstemmed Anal adenocarcinoma: case report, literature review and comparative survival analysis
title_short Anal adenocarcinoma: case report, literature review and comparative survival analysis
title_sort anal adenocarcinoma: case report, literature review and comparative survival analysis
topic Anorectal Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273449/
https://www.ncbi.nlm.nih.gov/pubmed/34244243
http://dx.doi.org/10.1136/bmjgast-2021-000661
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AT nagaranilb analadenocarcinomacasereportliteraturereviewandcomparativesurvivalanalysis
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