Selective Anti-melanoma Effect of Phosphothioated Aptamer Encapsulated by Neutral Cytidinyl/Cationic Lipids

BC15-31 is a DNA aptamer that targets heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1), which plays a crucial role in the process of pre-RNA maturation and is also essential for the rapid proliferation of tumor cells. In this research, we modified BC15-31 with a phosphorothioate (PS) backbone,...

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Detalles Bibliográficos
Autores principales: Wu, Jing, Wang, Shuhe, Li, Xiang, Zhang, Qi, Yang, Jie, Ma, Yuan, Guan, Zhu, Yang, Zhenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273494/
https://www.ncbi.nlm.nih.gov/pubmed/34262898
http://dx.doi.org/10.3389/fcell.2021.660233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273494/
https://www.ncbi.nlm.nih.gov/pubmed/34262898
http://dx.doi.org/10.3389/fcell.2021.660233

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