Cargando…

Punicalagin Attenuates Disturbed Flow-Induced Vascular Dysfunction by Inhibiting Force-Specific Activation of Smad1/5

BACKGROUND: Pathophysiological vascular remodeling in response to disturbed flow with low and oscillatory shear stress (OSS) plays important roles in atherosclerosis progression. Pomegranate extraction (PE) was reported having anti-atherogenic effects. However, whether it can exert a beneficial effe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anwaier, Gulinigaer, Lian, Guan, Ma, Gui-Zhi, Shen, Wan-Li, Lee, Chih-I, Lee, Pei-Ling, Chang, Zhan-Ying, Wang, Yun-Xia, Tian, Xiao-Yu, Gao, Xiao-Li, Chiu, Jeng-Jiann, Qi, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273543/ https://www.ncbi.nlm.nih.gov/pubmed/34262908 http://dx.doi.org/10.3389/fcell.2021.697539

Ejemplares similares

Mechanoresponsive Smad5 Enhances MiR-487a Processing to Promote Vascular Endothelial Proliferation in Response to Disturbed Flow
por: Wang, Wei-Li, et al.
Publicado: (2021)

Differential regulations of fibronectin and laminin in Smad2 activation in vascular endothelial cells in response to disturbed flow
por: Yang, Tung-Lin, et al.
Publicado: (2018)

Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia
por: Subkorn, Paweena, et al.
Publicado: (2021)

HYAL-2–WWOX–SMAD4 Signaling in Cell Death and Anticancer Response
por: Hsu, Li-Jin, et al.
Publicado: (2016)

Exosomes Released From Human Bone Marrow–Derived Mesenchymal Stem Cell Attenuate Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation in Mice
por: Li, Ke-Liang, et al.
Publicado: (2021)

Aberrant regulation of autophagy disturbs fibrotic liver regeneration after partial hepatectomy
por: Lian, Yuan-E., et al.
Publicado: (2022)

Noggin Overexpression Impairs the Development of Muscles, Tendons, and Aponeurosis in Soft Palates by Disrupting BMP-Smad and Shh-Gli1 Signaling
por: Deng, Jiamin, et al.
Publicado: (2021)

Hsa_Circ_0001860 Promotes Smad7 to Enhance MPA Resistance in Endometrial Cancer via miR-520h
por: Yuan, Shuang, et al.
Publicado: (2021)

The Role of SMAD2/3 in Human Embryonic Stem Cells
por: Yang, Jie, et al.
Publicado: (2020)

LncRNA MTX2-6 Suppresses Cell Proliferation by Acting as ceRNA of miR-574-5p to Accumulate SMAD4 in Esophageal Squamous Cell Carcinoma
por: Li, Jie, et al.
Publicado: (2021)

Role of TGF-β/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Differentiation
por: Gao, Yuhua, et al.
Publicado: (2019)

Force From Filaments: The Role of the Cytoskeleton and Extracellular Matrix in the Gating of Mechanosensitive Channels
por: Chuang, Yu-Chia, et al.
Publicado: (2022)

Azoxystrobin exposure impairs meiotic maturation by disturbing spindle formation in mouse oocytes
por: Gao, Wen, et al.
Publicado: (2022)

A Bibliometric Analysis Based on Web of Science: Current Perspectives and Potential Trends of SMAD7 in Oncology
por: Huang, Xueying, et al.
Publicado: (2022)

Corrigendum: Role of TGF-β/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Differentiation
por: Gao, Yuhua, et al.
Publicado: (2020)

Conditioned medium from human cord blood mesenchymal stem cells attenuates age-related immune dysfunctions
por: Sun, Bo, et al.
Publicado: (2023)

Disturb mitochondrial associated proteostasis: Neurodegeneration and imperfect ageing
por: Jagtap, Yuvraj Anandrao, et al.
Publicado: (2023)

β-Ecdysterone Enhanced Bone Regeneration Through the BMP-2/SMAD/RUNX2/Osterix Signaling Pathway
por: Yan, Cai-Ping, et al.
Publicado: (2022)

Upregulation of Extracellular Vesicles-Encapsulated miR-132 Released From Mesenchymal Stem Cells Attenuates Ischemic Neuronal Injury by Inhibiting Smad2/c-jun Pathway via Acvr2b Suppression
por: Feng, Bin, et al.
Publicado: (2021)

Circ0083429 Regulates Osteoarthritis Progression via the Mir-346/SMAD3 Axis
por: Yao, Teng, et al.
Publicado: (2021)

Physiological and Immune Functions of Punicalagin
por: Venusova, Eva, et al.
Publicado: (2021)

The Role of Disturbed Mg Homeostasis in Chronic Kidney Disease Comorbidities
por: Rodelo-Haad, Cristian, et al.
Publicado: (2020)

VAMP3 and SNAP23 as Potential Targets for Preventing the Disturbed Flow-Accelerated Thrombus Formation
por: Zhu, Juan-Juan, et al.
Publicado: (2020)

Transcriptomic analysis of Bursaphelenchus xylophilus treated by a potential phytonematicide, punicalagin
por: Guo, Qun-Qun, et al.
Publicado: (2020)

Ufbp1, a Key Player of Ufm1 Conjugation System, Protects Against Ketosis-Induced Liver Injury via Suppressing Smad3 Activation
por: Chen, Fanghui, et al.
Publicado: (2021)

Punicalagin Targets Atherosclerosis: Gene Expression Profiling of THP-1 Macrophages Treated with Punicalagin and Molecular Docking
por: Huwait, Etimad, et al.
Publicado: (2022)

Punicalagin attenuates ventricular remodeling after acute myocardial infarction via regulating the NLRP3/caspase-1 pathway
por: Peng, Jian-fei, et al.
Publicado: (2023)

Ectopic Splicing Disturbs the Function of Xist RNA to Establish the Stable Heterochromatin State
por: Matsuura, Ruka, et al.
Publicado: (2021)

Adiponectin Modified BMSCs Alleviate Heart Fibrosis via Inhibition TGF-beta1/Smad in Diabetic Rats
por: Meng, Ke, et al.
Publicado: (2021)

Parabolic relationship between SMAD3 expression level and the reprogramming efficiency of goat induced mammary epithelial cells
por: Wu, Yulian, et al.
Publicado: (2022)

Punicalagin Attenuates LPS-Induced Inflammation and ROS Production in Microglia by Inhibiting the MAPK/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation
por: Lo, Jung, et al.
Publicado: (2022)

Regulation of erythroid differentiation in K562 cells by the EPAS1-IRS2 axis under hypoxic conditions
por: Gao, Zhan, et al.
Publicado: (2023)

Integrative 5-Methylcytosine Modification Immunologically Reprograms Tumor Microenvironment Characterizations and Phenotypes of Clear Cell Renal Cell Carcinoma
por: Xu, Wenhao, et al.
Publicado: (2021)

Forces to Drive Neuronal Migration Steps
por: Minegishi, Takunori, et al.
Publicado: (2020)

Cytoskeleton Force Exertion in Bulk Cytoplasm
por: Xie, Jing, et al.
Publicado: (2020)

Force Transmission in Disordered Fibre Networks
por: Ruiz-Franco, José, et al.
Publicado: (2022)

Inhibition of TGF-β/Smad3 Signaling Disrupts Cardiomyocyte Cell Cycle Progression and Epithelial–Mesenchymal Transition-Like Response During Ventricle Regeneration
por: Peng, Yuanyuan, et al.
Publicado: (2021)

Corrigendum: Adiponectin modified BMSCs alleviate heart fibrosis via inhibition TGF-beta1/smad in diabetic rats
por: Meng, Ke, et al.
Publicado: (2023)

Retinoic Acid Signaling Plays a Crucial Role in Excessive Caffeine Intake-Disturbed Apoptosis and Differentiation of Myogenic Progenitors
por: Wu, Nian, et al.
Publicado: (2021)

Atheroprotective Mechanisms of Tilianin by Inhibiting Inflammation Through Down-Regulating NF-κB Pathway and Foam Cells Formation
por: Shen, Wanli, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lrodrguecq7aa9n3jah0e4jvim