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Recurrent COVID-19 infection in a health care worker: a case report

BACKGROUND: Recurrent coronavirus disease 2019 (COVID-19) infection is an emerging problem and may prove to be one of the greatest problems in controlling the pandemic in the future. Recurrent infections can be due to reactivation of dormant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-...

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Autores principales: Garg, Jaya, Agarwal, Jyotsna, Das, Anupam, Sen, Manodeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273561/
https://www.ncbi.nlm.nih.gov/pubmed/34253225
http://dx.doi.org/10.1186/s13256-021-02881-8
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author Garg, Jaya
Agarwal, Jyotsna
Das, Anupam
Sen, Manodeep
author_facet Garg, Jaya
Agarwal, Jyotsna
Das, Anupam
Sen, Manodeep
author_sort Garg, Jaya
collection PubMed
description BACKGROUND: Recurrent coronavirus disease 2019 (COVID-19) infection is an emerging problem and may prove to be one of the greatest problems in controlling the pandemic in the future. Recurrent infections can be due to reactivation of dormant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or reinfection with similar or different strains of SARS-CoV-2. CASE PRESENTATION: Here we present an interesting case of a health care worker working as a laboratory assistant at a COVID-19 laboratory who developed recurrent COVID-19 infection. He did not develop an immune response after the first episode of COVID-19; however, immunoglobulin G (IgG) antibodies were detected after the second episode. CONCLUSIONS: Through this case, we discuss the concept of reactivation and reinfection in the post-COVID period. We suggest that standard guidelines should be established to check for viral shedding and immune response among cured cases of COVID-19 after discharge via serial real-time polymerase chain reaction (RT-PCR) testing and IgG antibody detection. Further, strict hygiene practices should be stressed to these patients with possibility of COVID-19 recurrence.
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spelling pubmed-82735612021-07-12 Recurrent COVID-19 infection in a health care worker: a case report Garg, Jaya Agarwal, Jyotsna Das, Anupam Sen, Manodeep J Med Case Rep Case Report BACKGROUND: Recurrent coronavirus disease 2019 (COVID-19) infection is an emerging problem and may prove to be one of the greatest problems in controlling the pandemic in the future. Recurrent infections can be due to reactivation of dormant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or reinfection with similar or different strains of SARS-CoV-2. CASE PRESENTATION: Here we present an interesting case of a health care worker working as a laboratory assistant at a COVID-19 laboratory who developed recurrent COVID-19 infection. He did not develop an immune response after the first episode of COVID-19; however, immunoglobulin G (IgG) antibodies were detected after the second episode. CONCLUSIONS: Through this case, we discuss the concept of reactivation and reinfection in the post-COVID period. We suggest that standard guidelines should be established to check for viral shedding and immune response among cured cases of COVID-19 after discharge via serial real-time polymerase chain reaction (RT-PCR) testing and IgG antibody detection. Further, strict hygiene practices should be stressed to these patients with possibility of COVID-19 recurrence. BioMed Central 2021-07-12 /pmc/articles/PMC8273561/ /pubmed/34253225 http://dx.doi.org/10.1186/s13256-021-02881-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Garg, Jaya
Agarwal, Jyotsna
Das, Anupam
Sen, Manodeep
Recurrent COVID-19 infection in a health care worker: a case report
title Recurrent COVID-19 infection in a health care worker: a case report
title_full Recurrent COVID-19 infection in a health care worker: a case report
title_fullStr Recurrent COVID-19 infection in a health care worker: a case report
title_full_unstemmed Recurrent COVID-19 infection in a health care worker: a case report
title_short Recurrent COVID-19 infection in a health care worker: a case report
title_sort recurrent covid-19 infection in a health care worker: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273561/
https://www.ncbi.nlm.nih.gov/pubmed/34253225
http://dx.doi.org/10.1186/s13256-021-02881-8
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