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Single-Dose Immunization With a Chimpanzee Adenovirus-Based Vaccine Induces Sustained and Protective Immunity Against SARS-CoV-2 Infection

The development of a safe and effective vaccine against SARS-CoV-2, the causative agent of pandemic coronavirus disease-2019 (COVID-19), is a global priority. Here, we aim to develop novel SARS-CoV-2 vaccines based on a derivative of less commonly used rare adenovirus serotype AdC68 vector. Three va...

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Detalles Bibliográficos
Autores principales: Li, Mingxi, Guo, Jingao, Lu, Shuaiyao, Zhou, Runhong, Shi, Hongyang, Shi, Xuanling, Cheng, Lin, Liang, Qingtai, Liu, Hongqi, Wang, Pui, Wang, Nan, Wang, Yifeng, Fu, Lili, Xing, Man, Wang, Ruoke, Ju, Bin, Liu, Li, Lau, Siu-Ying, Jia, Wenxu, Tong, Xin, Yuan, Lin, Guo, Yong, Qi, Hai, Zhang, Qi, Huang, Zhen, Chen, Honglin, Zhang, Zheng, Chen, Zhiwei, Peng, Xiaozhong, Zhou, Dongming, Zhang, Linqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273614/
https://www.ncbi.nlm.nih.gov/pubmed/34262569
http://dx.doi.org/10.3389/fimmu.2021.697074