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Abnormal function of telomere protein TRF2 induces cell mutation and the effects of environmental tumor-promoting factors

Recent studies have found that somatic gene mutations and environmental tumor-promoting factors are both indispensable for tumor formation. Telomeric repeat-binding factor (TRF)2 is the core component of the telomere shelterin complex, which plays an important role in chromosome stability and the ma...

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Detalles Bibliográficos
Autores principales: Wang, Zhengyi, Wu, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273685/
https://www.ncbi.nlm.nih.gov/pubmed/34278498
http://dx.doi.org/10.3892/or.2021.8135