Cargando…
A Novel HAGE/WT1-ImmunoBody(®) Vaccine Combination Enhances Anti-Tumour Responses When Compared to Either Vaccine Alone
Many cancers, including myeloid leukaemia express the cancer testis antigen (CTA) DDX43 (HAGE) and/or the oncogene Wilms’ tumour (WT1). Here we demonstrate that HAGE/WT1-ImmunoBody(®) vaccines derived T-cells can kill ex-vivo human CML cell lines expressing these antigens and significantly delay B16...
Autores principales: | Almshayakhchi, Rukaia, Nagarajan, Divya, Vadakekolathu, Jayakumar, Guinn, Barbara-Ann, Reeder, Stephen, Brentville, Victoria, Metheringham, Rachael, Pockley, A. Graham, Durrant, Lindy, McArdle, Stephanie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273701/ https://www.ncbi.nlm.nih.gov/pubmed/34262856 http://dx.doi.org/10.3389/fonc.2021.636977 |
Ejemplares similares
-
HAGE (DDX43) is a biomarker for poor prognosis and a predictor of chemotherapy response in breast cancer
por: Abdel-Fatah, T M A, et al.
Publicado: (2014) -
A Mutated Prostatic Acid Phosphatase (PAP) Peptide-Based Vaccine Induces PAP-Specific CD8(+) T Cells with Ex Vivo Cytotoxic Capacities in HHDII/DR1 Transgenic Mice
por: Vu, Pauline Le, et al.
Publicado: (2022) -
High Avidity Cytotoxic T Lymphocytes Can Be Selected into the Memory Pool but They Are Exquisitely Sensitive to Functional Impairment
por: Brentville, Victoria A., et al.
Publicado: (2012) -
Mr. William Pierce Hagee
Publicado: (1916) -
SCIB1, a huIgG1 antibody DNA vaccination, combined with PD-1 blockade induced efficient therapy of poorly immunogenic tumors
por: Xue, Wei, et al.
Publicado: (2016)