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Resveratrol protects intestinal epithelial cells against radiation-induced damage by promoting autophagy and inhibiting apoptosis through SIRT1 activation
Intrinsic autophagy is important for the maintenance of intestinal homeostasis and intestinal regeneration. Ionizing radiation suppresses intrinsic autophagy and reduces damage-induced regeneration in the intestine, resulting in intestinal injury. Resveratrol, a sirtuin 1 (SIRT1) agonist, promotes a...
Autores principales: | Qin, Haoren, Zhang, Heng, Zhang, Xipeng, Zhang, Shiwu, Zhu, Siwei, Wang, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273810/ https://www.ncbi.nlm.nih.gov/pubmed/33912959 http://dx.doi.org/10.1093/jrr/rrab035 |
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