NudC L279P Mutation Destabilizes Filamin A by Inhibiting the Hsp90 Chaperoning Pathway and Suppresses Cell Migration

Filamin A, the first discovered non-muscle actin filament cross-linking protein, plays a crucial role in regulating cell migration that participates in diverse cellular and developmental processes. However, the regulatory mechanism of filamin A stability remains unclear. Here, we find that nuclear d...

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Detalles Bibliográficos
Autores principales: Liu, Min, Xu, Zhangqi, Zhang, Cheng, Yang, Chunxia, Feng, Jiaxing, Lu, Yiqing, Zhang, Wen, Chen, Wenwen, Xu, Xiaoyang, Sun, Xiaoxia, Yang, Mingyang, Liu, Wei, Zhou, Tianhua, Yang, Yuehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273881/
https://www.ncbi.nlm.nih.gov/pubmed/34262899
http://dx.doi.org/10.3389/fcell.2021.671233

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