Development of [(18)F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism

[Image: see text] The purpose of this study was to synthesize a fluorine-18 labeled, highly selective aldosterone synthase (hCYP11B2) inhibitor, [(18)F]AldoView, and to assess its potential for the detection of aldosterone-producing adenomas (APAs) with positron emission tomography in patients with...

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Detalles Bibliográficos
Autores principales: Sander, Kerstin, Gendron, Thibault, Cybulska, Klaudia A., Sirindil, Fatih, Zhou, Junhua, Kalber, Tammy L., Lythgoe, Mark F., Kurzawinski, Tom R., Brown, Morris J., Williams, Bryan, Årstad, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273890/
https://www.ncbi.nlm.nih.gov/pubmed/34137616
http://dx.doi.org/10.1021/acs.jmedchem.1c00539

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