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Multi-drug-resistance efflux in cisplatin-naive and cisplatin-exposed A2780 ovarian cancer cells responds differently to cell culture dimensionality

A primary reason for chemotherapy failure is chemoresistance, which is driven by various mechanisms. Multi-drug resistance (MDR) is one such mechanism that is responsible for drug extrusion from the intracellular space. MDR can be intrinsic and thus, may pre-exist the first application of chemothera...

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Detalles Bibliográficos
Autores principales:	Koshkin, Vasilij, De Oliveira, Mariana Bleker, Peng, Chun, Ailles, Laurie E., Liu, Geoffrey, Covens, Allan, Krylov, Sergey N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273925/ https://www.ncbi.nlm.nih.gov/pubmed/34295468 http://dx.doi.org/10.3892/mco.2021.2323

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