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Elesclomol-induced increase of mitochondrial reactive oxygen species impairs glioblastoma stem-like cell survival and tumor growth
BACKGROUND: Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor in adults, characterized by a poor prognosis mainly due to recurrence and therapeutic resistance. It has been widely demonstrated that glioblastoma stem-like cells (GSCs), a subpopulation of tumor cells en...
Autores principales: | Buccarelli, Mariachiara, D’Alessandris, Quintino Giorgio, Matarrese, Paola, Mollinari, Cristiana, Signore, Michele, Cappannini, Andrea, Martini, Maurizio, D’Aliberti, Pierluigi, De Luca, Gabriele, Pedini, Francesca, Boe, Alessandra, Biffoni, Mauro, Pallini, Roberto, Ricci-Vitiani, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273992/ https://www.ncbi.nlm.nih.gov/pubmed/34253243 http://dx.doi.org/10.1186/s13046-021-02031-4 |
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