Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B

[Image: see text] A library of monosubstituted chalcones (1–17) bearing electron-donating and electron-withdrawing groups on both aromatic rings were selected. The cell viability on human tumor cell lines was evaluated first. The compounds unable to induce detectable cytotoxicity (1, 13, and 14) wer...

Descripción completa

Detalles Bibliográficos
Autores principales: Iacovino, Luca G., Pinzi, Luca, Facchetti, Giorgio, Bortolini, Beatrice, Christodoulou, Michael S., Binda, Claudia, Rastelli, Giulio, Rimoldi, Isabella, Passarella, Daniele, Di Paolo, Maria Luisa, Dalla Via, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274062/
https://www.ncbi.nlm.nih.gov/pubmed/34262643
http://dx.doi.org/10.1021/acsmedchemlett.1c00238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274062/
https://www.ncbi.nlm.nih.gov/pubmed/34262643
http://dx.doi.org/10.1021/acsmedchemlett.1c00238

Ejemplares similares