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Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B
[Image: see text] A library of monosubstituted chalcones (1–17) bearing electron-donating and electron-withdrawing groups on both aromatic rings were selected. The cell viability on human tumor cell lines was evaluated first. The compounds unable to induce detectable cytotoxicity (1, 13, and 14) wer...
Autores principales: | Iacovino, Luca G., Pinzi, Luca, Facchetti, Giorgio, Bortolini, Beatrice, Christodoulou, Michael S., Binda, Claudia, Rastelli, Giulio, Rimoldi, Isabella, Passarella, Daniele, Di Paolo, Maria Luisa, Dalla Via, Lisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274062/ https://www.ncbi.nlm.nih.gov/pubmed/34262643 http://dx.doi.org/10.1021/acsmedchemlett.1c00238 |
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