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Unilateral Limited Laminectomy for Debridement to Treat Localized Short‐Segment Lumbosacral Spinal Tuberculosis: A Retrospective Case Series

OBJECTIVE: This study aimed to investigate the clinical effects of surgically treating lumbosacral tuberculosis with a modified posterior unilateral limited laminectomy method for debridement. METHODS: This retrospective study enrolled a total of 26 patients who were administered in our institution...

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Autores principales: Li, Miao, Huang, Jianjun, Chen, Jinbiao, Liu, Shaohua, Deng, Zhansheng, Hu, Jianzhong, Cao, Yong, Wu, Tianding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274194/
https://www.ncbi.nlm.nih.gov/pubmed/33942987
http://dx.doi.org/10.1111/os.12940
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author Li, Miao
Huang, Jianjun
Chen, Jinbiao
Liu, Shaohua
Deng, Zhansheng
Hu, Jianzhong
Cao, Yong
Wu, Tianding
author_facet Li, Miao
Huang, Jianjun
Chen, Jinbiao
Liu, Shaohua
Deng, Zhansheng
Hu, Jianzhong
Cao, Yong
Wu, Tianding
author_sort Li, Miao
collection PubMed
description OBJECTIVE: This study aimed to investigate the clinical effects of surgically treating lumbosacral tuberculosis with a modified posterior unilateral limited laminectomy method for debridement. METHODS: This retrospective study enrolled a total of 26 patients who were administered in our institution from January 2010 to December 2016, diagnosed with lumbosacral tuberculosis at the L5/S1 level, and underwent one‐stage posterior unilateral limited laminectomy as surgical treatment for debridement, allograft of cortical bone grafting, and fixation. The erythrocyte sedimentation rate (ESR), C‐reactive protein (CRP) level, visual analog scale (VAS) score, Oswestry Disability Index (ODI), and lumbosacral angle (LA, Cobb's method) were statistically compared, and the American Spinal Injury Association Impairment (ASIA) Scale was compared between the preoperative and postoperative time points to evaluate the clinical outcomes. RESULTS: All 26 patients were observed during the follow‐up period, and the mean follow‐up time was 1.3 ± 0.42 years. The mean age was 56 ± 7.4 years old. The average operation time was 118.1 ± 17.5 min, and the mean bleeding volume was 513.0 ± 79.6 mL. There were no intraoperative complications or tuberculous sinus, and two cases experienced hypostatic pneumonia during hospitalization, which resolved with responsive antibiotics and symptomatic supportive treatment. At the final follow‐up, there was no recurrence of tuberculosis, and the ESR (11.8 ± 1.8 mm/h) and CRP (3.0 ± 1.0 mg/L) levels in all patients had returned to normal. The patients with neurologic deficits had improved, and the mean ODI was 79.9 ± 10.6 (87–62) preoperatively and significantly decreased to 20.5 ± 5.7 (11–29) at the final follow‐up (P < 0.01). ASIA scale scores were improved by 1~2 grades at the last follow‐up. The patients' pain levels were significantly alleviated; the mean VAS score declined to 1.2 ± 0.4 (0–2.5) at the final follow‐up compared to 7.5 ± 1.6 (6.5–8.5) preoperatively (P < 0.01). All patients achieved bony graft fusion at an average time of 6.8 ± 1.2 months. Physiological lumbar lordosis was significantly improved, and the mean LA before operation was 17.6° ± 2.1°, which was significantly different from the postoperative LA (29.3° ± 7.4°, P < 0.01) at the final follow up. The LA (27.1° ± 5.5°, P = 0.15) slightly rebounded but without significance compared to the postoperative level. CONCLUSION: Only posterior approach by unilateral limited laminectomy for debridement could be served as an effective and safe method to treat short‐segment lumbosacral tuberculosis without extensive anterior sacral and gravitation abscesses.
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spelling pubmed-82741942021-07-14 Unilateral Limited Laminectomy for Debridement to Treat Localized Short‐Segment Lumbosacral Spinal Tuberculosis: A Retrospective Case Series Li, Miao Huang, Jianjun Chen, Jinbiao Liu, Shaohua Deng, Zhansheng Hu, Jianzhong Cao, Yong Wu, Tianding Orthop Surg Clinical Articles OBJECTIVE: This study aimed to investigate the clinical effects of surgically treating lumbosacral tuberculosis with a modified posterior unilateral limited laminectomy method for debridement. METHODS: This retrospective study enrolled a total of 26 patients who were administered in our institution from January 2010 to December 2016, diagnosed with lumbosacral tuberculosis at the L5/S1 level, and underwent one‐stage posterior unilateral limited laminectomy as surgical treatment for debridement, allograft of cortical bone grafting, and fixation. The erythrocyte sedimentation rate (ESR), C‐reactive protein (CRP) level, visual analog scale (VAS) score, Oswestry Disability Index (ODI), and lumbosacral angle (LA, Cobb's method) were statistically compared, and the American Spinal Injury Association Impairment (ASIA) Scale was compared between the preoperative and postoperative time points to evaluate the clinical outcomes. RESULTS: All 26 patients were observed during the follow‐up period, and the mean follow‐up time was 1.3 ± 0.42 years. The mean age was 56 ± 7.4 years old. The average operation time was 118.1 ± 17.5 min, and the mean bleeding volume was 513.0 ± 79.6 mL. There were no intraoperative complications or tuberculous sinus, and two cases experienced hypostatic pneumonia during hospitalization, which resolved with responsive antibiotics and symptomatic supportive treatment. At the final follow‐up, there was no recurrence of tuberculosis, and the ESR (11.8 ± 1.8 mm/h) and CRP (3.0 ± 1.0 mg/L) levels in all patients had returned to normal. The patients with neurologic deficits had improved, and the mean ODI was 79.9 ± 10.6 (87–62) preoperatively and significantly decreased to 20.5 ± 5.7 (11–29) at the final follow‐up (P < 0.01). ASIA scale scores were improved by 1~2 grades at the last follow‐up. The patients' pain levels were significantly alleviated; the mean VAS score declined to 1.2 ± 0.4 (0–2.5) at the final follow‐up compared to 7.5 ± 1.6 (6.5–8.5) preoperatively (P < 0.01). All patients achieved bony graft fusion at an average time of 6.8 ± 1.2 months. Physiological lumbar lordosis was significantly improved, and the mean LA before operation was 17.6° ± 2.1°, which was significantly different from the postoperative LA (29.3° ± 7.4°, P < 0.01) at the final follow up. The LA (27.1° ± 5.5°, P = 0.15) slightly rebounded but without significance compared to the postoperative level. CONCLUSION: Only posterior approach by unilateral limited laminectomy for debridement could be served as an effective and safe method to treat short‐segment lumbosacral tuberculosis without extensive anterior sacral and gravitation abscesses. John Wiley & Sons Australia, Ltd 2021-05-04 /pmc/articles/PMC8274194/ /pubmed/33942987 http://dx.doi.org/10.1111/os.12940 Text en © 2021 The Authors. Orthopaedic Surgery published by Chinese Orthopaedic Association and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Clinical Articles
Li, Miao
Huang, Jianjun
Chen, Jinbiao
Liu, Shaohua
Deng, Zhansheng
Hu, Jianzhong
Cao, Yong
Wu, Tianding
Unilateral Limited Laminectomy for Debridement to Treat Localized Short‐Segment Lumbosacral Spinal Tuberculosis: A Retrospective Case Series
title Unilateral Limited Laminectomy for Debridement to Treat Localized Short‐Segment Lumbosacral Spinal Tuberculosis: A Retrospective Case Series
title_full Unilateral Limited Laminectomy for Debridement to Treat Localized Short‐Segment Lumbosacral Spinal Tuberculosis: A Retrospective Case Series
title_fullStr Unilateral Limited Laminectomy for Debridement to Treat Localized Short‐Segment Lumbosacral Spinal Tuberculosis: A Retrospective Case Series
title_full_unstemmed Unilateral Limited Laminectomy for Debridement to Treat Localized Short‐Segment Lumbosacral Spinal Tuberculosis: A Retrospective Case Series
title_short Unilateral Limited Laminectomy for Debridement to Treat Localized Short‐Segment Lumbosacral Spinal Tuberculosis: A Retrospective Case Series
title_sort unilateral limited laminectomy for debridement to treat localized short‐segment lumbosacral spinal tuberculosis: a retrospective case series
topic Clinical Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274194/
https://www.ncbi.nlm.nih.gov/pubmed/33942987
http://dx.doi.org/10.1111/os.12940
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