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Pouring petrol on the flames: Using oncolytic virotherapies to enhance tumour immunogenicity

Oncolytic viruses possess the ability to infect, replicate and lyse malignantly transformed tumour cells. This oncolytic activity amplifies the therapeutic advantage and induces a form of immunogenic cell death, characterized by increased CD8( +) T‐cell infiltration into the tumour microenvironment....

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Detalles Bibliográficos
Autores principales: Teijeira Crespo, Alicia, Burnell, Stephanie, Capitani, Lorenzo, Bayliss, Rebecca, Moses, Elise, Mason, Georgina H., Davies, James A., Godkin, Andrew J., Gallimore, Awen M., Parker, Alan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274202/
https://www.ncbi.nlm.nih.gov/pubmed/33638871
http://dx.doi.org/10.1111/imm.13323