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A potent endocytosis inhibitor Ikarugamycin up-regulates TNF production

Ikarugamycin (IK) is an antibiotic which has been reported to have a variety of functions, such as inhibition of clathrin-mediated endocytosis (CME), anti-tumor effects and regulation of the immune system. Whether IK influences cytokine production is poorly understood. We have investigated the relat...

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Detalles Bibliográficos
Autores principales: Minamidate, Ai, Onizawa, Michio, Saito, Chikako, Hikichi, Rie, Mochimaru, Tomoaki, Murakami, Mai, Sakuma, Chiharu, Asakawa, Takehito, Hiraoka, Yuichi, Oshima, Shigeru, Nagaishi, Takashi, Tsuchiya, Kiichiro, Ohira, Hiromasa, Okamoto, Ryuichi, Watanabe, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274290/
https://www.ncbi.nlm.nih.gov/pubmed/34286109
http://dx.doi.org/10.1016/j.bbrep.2021.101065