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Utilizing feline oral squamous cell carcinoma patients to develop NQO1-targeted therapy
Developing effective therapies for the treatment of advanced head-and-neck squamous cell carcinoma (HNSCC) remains a major challenge, and there is a limited landscape of effective targeted therapies on the horizon. NAD(P)H:quinone oxidoreductase 1 (NQO1) is a 2-electron reductase that is overexpress...
Autores principales: | Lundberg, Alycen P., Boudreau, Matthew W., Selting, Kim A., Chatkewitz, Lindsay E., Samuelson, Jonathan, Francis, Joshua M., Parkinson, Elizabeth I., Barger, Anne M., Hergenrother, Paul J., Fan, Timothy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274297/ https://www.ncbi.nlm.nih.gov/pubmed/34246985 http://dx.doi.org/10.1016/j.neo.2021.06.008 |
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