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Endothelial arginase 2 mediates retinal ischemia/reperfusion injury by inducing mitochondrial dysfunction
OBJECTIVE: Retinal ischemic disease is a major cause of vision loss. Current treatment options are limited to late-stage diseases, and the molecular mechanisms of the initial insult are not fully understood. We have previously shown that the deletion of the mitochondrial arginase isoform, arginase 2...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274341/ https://www.ncbi.nlm.nih.gov/pubmed/34139341 http://dx.doi.org/10.1016/j.molmet.2021.101273 |