Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease

Disseminated histoplasmosis is a life-threatening disease usually seen in immunocompromised patients living in endemic areas. We present an apparently immunocompetent patient with gastrointestinal histoplasmosis who was initially diagnosed with biopsy-proven Crohn’s disease. Following discontinuatio...

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Autores principales: Shojaei, Esfandiar, Walsh, Joanna C, Sangle, Nikhil, Yan, Brian, Silverman, Michael S, Hosseini-Moghaddam, Seyed M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
ID Teaching Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274358/
https://www.ncbi.nlm.nih.gov/pubmed/34262987
http://dx.doi.org/10.1093/ofid/ofab249
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author Shojaei, Esfandiar
Walsh, Joanna C
Sangle, Nikhil
Yan, Brian
Silverman, Michael S
Hosseini-Moghaddam, Seyed M
author_facet Shojaei, Esfandiar
Walsh, Joanna C
Sangle, Nikhil
Yan, Brian
Silverman, Michael S
Hosseini-Moghaddam, Seyed M
author_sort Shojaei, Esfandiar
collection PubMed
description Disseminated histoplasmosis is a life-threatening disease usually seen in immunocompromised patients living in endemic areas. We present an apparently immunocompetent patient with gastrointestinal histoplasmosis who was initially diagnosed with biopsy-proven Crohn’s disease. Following discontinuation of anti-inflammatory drugs and institution of antifungal therapy, his gastrointestinal illness completely improved. Specific fungal staining should be routinely included in histopathologic assessment of tissue specimens diagnosed as Crohn’s disease.
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spelling pubmed-82743582021-07-13 Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease Shojaei, Esfandiar Walsh, Joanna C Sangle, Nikhil Yan, Brian Silverman, Michael S Hosseini-Moghaddam, Seyed M Open Forum Infect Dis ID Teaching Cases Disseminated histoplasmosis is a life-threatening disease usually seen in immunocompromised patients living in endemic areas. We present an apparently immunocompetent patient with gastrointestinal histoplasmosis who was initially diagnosed with biopsy-proven Crohn’s disease. Following discontinuation of anti-inflammatory drugs and institution of antifungal therapy, his gastrointestinal illness completely improved. Specific fungal staining should be routinely included in histopathologic assessment of tissue specimens diagnosed as Crohn’s disease. Oxford University Press 2021-05-16 /pmc/articles/PMC8274358/ /pubmed/34262987 http://dx.doi.org/10.1093/ofid/ofab249 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle ID Teaching Cases
Shojaei, Esfandiar
Walsh, Joanna C
Sangle, Nikhil
Yan, Brian
Silverman, Michael S
Hosseini-Moghaddam, Seyed M
Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease
title Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease
title_full Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease
title_fullStr Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease
title_full_unstemmed Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease
title_short Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease
title_sort gastrointestinal histoplasmosis mimicking crohn’s disease
topic ID Teaching Cases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274358/
https://www.ncbi.nlm.nih.gov/pubmed/34262987
http://dx.doi.org/10.1093/ofid/ofab249
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