CTG-Repeat Detection in Primary Human Myoblasts of Myotonic Dystrophy Type 1

Myotonic dystrophy type 1 (DM1) is an autosomal dominant multisystemic disorder caused by unstable CTG-repeat expansions in the DMPK gene. Tissue mosaicism has been described for the length of these repeat expansions. The most obvious affected tissue is skeletal muscle, making it the first target fo...

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Detalles Bibliográficos
Autores principales: Hintze, Stefan, Mensel, Raphaela, Knaier, Lisa, Schoser, Benedikt, Meinke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274452/
https://www.ncbi.nlm.nih.gov/pubmed/34262431
http://dx.doi.org/10.3389/fnins.2021.686735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274452/
https://www.ncbi.nlm.nih.gov/pubmed/34262431
http://dx.doi.org/10.3389/fnins.2021.686735

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